Introduction: Mohs Micrographic Surgery is a well-known and established method in the United States, and is currently considered the gold standard treatment in many cases involving cutaneous neoplasias. Since it was first described by Dr. Frederic E. Mohs, the micrographic surgery technique has been continuously changed and adapted to better suit the daily life needs of dermatologic surgeons. This article examines different and innovative Mohs Micrographic Surgery techniques.

Keywords: MOHS SURGERY, CARCINOMA, BASAL CELL, CARCINOMA, SQUAMOUS CELL

Introduction: Dermatoscopy can help practitioners analyze details that are imperceptible to the naked eye, such as basal cell carcinoma arboriform vascularization patterns, which can b e linked to the tumoral limit. Clinical examinations might yet fail in the early detection and demarcation of the extension of such lesions.
Objective: To study the use of dermatoscopy in basal cell carcinomas, aiming at early detection and delimitation of their extension. Method: Basal cell carcinomas (n = 123) were studied prospectively and not randomly, using dermatoscopy, at the author''''''''s private practice. Suspect areas, mainly the nose, underwent dermatoscopic scanning. If the vascular pattern was identified, the tumor was delimited by dermatoscopy, and the incision was carried out using that marking. Surgical margins were checked using conventional cuts, cross sections or micrographic surgery.
Results:The vast majority of the tumors (92%) were located in the face, of which 59% were not well delimited, 21% were well delimited, and 20% were clinically undetectable. Although the vascular pattern was not observed in 18% of the tumors, in cases with a positive identification, it correctly delimited the tumors in 84% of cases (of which 44% were verified with conventional sampling, 48% with micrographic surgery and 8% with cross sections).
Conclusion: Dermatoscopy is an important tool in the early detection and delimitation of the superficial extension of basal cell carcinomas, and is helpful in the surgical planning and clinical control of such lesions.

Keywords: DERMOSCOPY, CARCINOMA, BASAL CELL, MOHS SURGERY, BLOOD VESSELS, CAPILLARIES

A case of pigmented basocellular carcinoma clinically mimicking a malignant lentigo melanoma in the temporal region of a black female patient is reported. Basal cell carcinoma rarely occurs in black patients. When present, however, it is the second most common malignant skin neoplasia, and is usually pigmented. When the face is affected in such patients, it is difficult to differentiate between malignant lentigo melanoma and basal cell carcinoma. Dermatoscopy is a very helpful diagnostic tool in these cases.

Keywords: CARCINOMA, BASAL CELL, MELANOMA, DERMOSCOPY

Dermoscopy is increasingly used to diagnose non-melanocytic skin tumors. Basal cell carcinoma presents some highly suggestive structures for its diagnosis. The presence of chrysalides-like structures is also frequently found in other benign and malignant skin tumors, and their significance in basal cell carcinoma has yet to be determined. HPV is a virus with oncogenic potential and its involvement in the pathogenesis of basal cell carcinomas is also not yet clearly understood.

Keywords: CARCINOMA, BASAL CELL, DERMOSCOPY, ONCOGENES

Solitary pink lesions of the face may have nonspecific dermoscopic patterns, and are thus deemed difficult to diagnose. Differential diagnoses to consider are: actinic keratosis, squamous cell carcinoma, basal cell carcinoma, and amelanotic melanoma. Confocal microscopy can be used as an auxiliary clinical examination in their diagnosis and in determining the most significant sites for carrying out a biopsy. The authors describe a case that illustrates the usefulness of a confocal microscopy examination in pink lesions.

Keywords: DERMOSCOPY, MICROSCOPY, CONFOCAL, CARCINOMA, BASAL CELL, KERATOSIS ACTINIC

Introduction: The reconstruction of surgical defects resulting from the excision of tumors in the nose is a challenge for dermatologic surgeons due to its rigid structure and low mobility. The Mohs Micrographic Surgery technique allows the preservation of healthy tissue and leads to a smaller surgical wound. Objective: To demonstrate techniques for surgical correction of defects after removal of tumors of the nose through Mohs Micrographic Surgery, according to the anatomical location of the tumor. Methods: Descriptive study of patients operated on using Mohs Micrographic Surgery during the period 1996-2010. Patient images taken pre-, intra-, and post-operatively were analyzed with the aim of classifying the defect's anatomic location and the type of surgical reconstruction adopted. Results: 170 patients (totaling 203 lesions) were included in the study. The most common locations for tumors were (in descending order): nasal ala, dorsum, tip, and lateral wall. The advancement flap was the most common reconstruction type for lesions located in the lateral wall and in the nasal ala. Grafts were most often used in lesions located in the tip of the nose. Grafts and advancement flaps were more frequently used in the dorsum of the nose. Conclusions: The parameters that provide guidance on choosing the best reconstruction method must take into consideration the size and location of the surgical defect.

Keywords: MOHS SURGERY, CARCINOMA, BASAL CELL, CARCINOMA, SQUAMOUS CELL

Introduction: Mohs micrographic surgery is a treatment option that increases the cure rate in various types of skin cancer, offering greater tissue preservation and lower recurrence rates. Objective: To describe clinically and histologically the tumors operated on with Mohs micrographic surgery, and to draw correlations to the number of stages and the type of surgical reconstruction performed. The operations were performed at a private clinic in the municipality of Rio de Janeiro, Brazil that is a specialist center for this technique. Methods: Retrospective, observational, cross-sectional/transversal study was carried out based on the review of medical records. Results: A study was conducted of 93 tumors in 84 patients, operated on between April 2010 and August 2012, and followed up with until August 2013 (12 to 42 months). Findings: 47.61% of patients were men and 52.38% were women, the mean age was 62.89 years; predominant phototypes: II (44%) and III (43%); 6 cases (6.45%) of squamous cell carcinoma, 87 (93.54%) of basal cell carcinoma; 74.19% were primary tumors; the nose was the most frequent site (46.24%); a single surgical stage was performed in most cases, with flaps (44%) being the more frequently performed type of closure. There was recurrence in one patient, who required reoperation in October 2012 and followed without new recurrence. Conclusions: Mohs surgery has proven effective with high cure rates and a minimal recurrence rate, especially in lesions located in the face's H area of risk.

Keywords: MOHS SURGRY, CARCINOMA, BASAL CELL, CARCINOMA, SQUAMOUS CELL.

We report a case of pigmented Bowen's disease in the periungual region treated with Mohs micrographic surgery. Bowen's disease is a squamous cell carcinoma in situ. Although it is a common condition, the pigmented form is rarer, with periungual localization being even more uncommon. Pigmented Bowen's disease presents clinically as a non-uniform, desquamous or verrucous brownish lesion, and it is often confused with other diseases (pigmented actinic keratosis, seborrheic keratosis, melanoma, basal cell carcinoma, nevus). Dermoscopy is of great diagnostic and therapeutic value and is important in the evaluation of recurrence.

Keywords: BOWEN'S DISEASE; CARCINOMA, SQUAMOUS CELL; DERMOSCOPY

Diagnosing basal cell carcinomas, both clinically and dermoscopically, is part of most dermatologists' daily routine. However, tumors of this lineage, when densely pigmented, can be a challenge for the physician and surgeon. Dermoscopic features typical of melanocytic lesions may be present in these carcinomas, and the similarity with melanoma results in a real dilemma. More in-depth knowledge on this topic can make a difference in the management of these cases.

Keywords: Carcinoma, Basal cell; Dermoscopia; Diagnosis; Melanoma

The cuniculatum carcinoma is a rare, slow-growth, local aggressive subtype of the squamous cell carcinoma, presented as a verrucous lesion with a low metastasis capacity. Its histopathology shows keratin-filled crypts, and its etiology is linked with HPV, especially 11 and 16 subtypes. The treatment of choice is surgical excision, followed by regular monitoring due to the high risk of local recurrence. We report a case of a woman with Cuniculatum carcinoma treated with surgery with perioperative frozen section procedure, graft, and good evolution.

Keywords: Carcinoma; Carcinoma, Squamous Cell; Foot

Basal cell carcinoma over the tattoo region has been poorly reported in the literature, with a total of 13 cases. All cases describe the clinical aspect of the lesion and its pathogenesis but do not characterize the dermoscopy. We report two cases of basal cell carcinoma on tattoos with clinical and dermoscopy features, treated with Mohs micrographic surgery. It was challenging to establish the tumor’s clinical and dermoscopic margins due to the tattoo’s exogenous pigment.

Keywords: Carcinoma, Basal cell; Dermoscopy; Tattooing; Mohs surgery

INTRODUCTION: Basal cell carcinoma is the most common non-melanoma malignancy in humans. Its superficial variant has specificities that can represent a diagnostic and therapeutic challenge.
OBJECTIVE: To describe the epidemiological profile of patients with superficial basal cell carcinoma (SBCC) treated at a reference service and to correlate, statistically, clinical, dermoscopic, and anatomopathological characteristics.
METHODS: Observational, analytical, cross-sectional study conducted by collecting data from patients with suspected SBCC between November 2019 and October 2020.
RESULTS: In total, we confirmed 25 lesions as SBCC. They were more frequent in women, in the head and neck, and with a diameter of less than 1 cm. We also observed, in clinical characteristics, a predominance of individuals over 60 years old and with phototypes II and III. The anatomopathological examination observed some pigmentation in the lesions evaluated and a predominance of intra-epidermal keratinocytes in lesions with maple leaf-like areas in dermoscopy.
CONCLUSIONS: SBCC can present clinically as a pigmented lesion, affecting more the head and neck regions. Lighter skin phototypes are more likely to have SBCC with pigmented dermoscopic structures. Intra-epidermal keratinocytes possibly correlate with the formation of maple leaf structures.

Keywords: Basal cell carcinoma; Dermoscopy; Epidemiology; Skin Neoplasms; Pathology

Basal cell carcinoma (BCC) is more common in the lower eyelid region when it affects the periorbital region. It occurs predominantly in men between 50-70 years and has a high recurrence rate. Although it rarely metastasizes, orbital invasion can occur. This study aims to present a case of pigmented BCC of unusual location. The location of BCC in the upper eyelid region is rare, and dermoscopy is essential to distinguish it from its primary differential diagnoses.

Keywords: Basal cell carcinoma; Dermoscopy; Eyelid Neoplasms

INTRODUCTION: Seborrheic keratosis (SK) has the typical pigmented dermoscopy features such as fissures and ridges, fat fingers, and cerebriform patterns. Here we describe a case where pigmented columns (PC) were visualized on SK’s dermoscopy associated with a squamous cell carcinoma (SCC). Case presentation: We report a case of a lesion whose dermoscopy showed PC. Histopathological report showed well-differentiated SCC and associated SK. Discussion: The PC was visualized in an area of dendritic melanocytes in the epidermis, correlating with the pigmented SK component of the lesion. To our knowledge, this is the first time PC is described in SK´s dermoscopy.

Keywords: Carcinoma squamous cell; Dermoscopy; Skin neoplasms.

INTRODUCTION: Actinic keratoses are premalignant lesions with a risk of transformation to invasive squamous cell carcinoma. There is no identified correlation between clinical classification and histological grade of these lesions.
OBJECTIVES: To correlate the clinical characteristics of actinic keratoses of the forearms and back of the hands with the degree of histological atypia (Keratinocyte Intraepidermal Neoplasia); to develop and validate a clinical severity scale correlated with the histological grade of actinic keratoses.
METHODS: Cross-sectional study with 162 actinic keratoses clinically evaluated for diameter, erythema, infiltration, hyperkeratosis, and exulceration and 34 lesions with different patterns were biopsied. Clinical features were correlated with the degree of histological atypia and p53 and Ki-67 expression.
RESULTS: Only the diameter of the lesions was significantly correlated with the degree of atypia (p=0.04), and only the erythema, hyperkeratosis, and the diameter linked with the immunohistochemical markings. A clinical score including diameter, hyperkeratosis, and exulceration was developed, which associated significantly with the degree of atypia (Spearman’s Rho=0.43; p=0.01).
CONCLUSIONS: A score composed of diameter, hyperkeratosis, and exulceration correlated with the histological grade of actinic keratoses of the upper limbs was developed.

Keywords: Carcinoma in situ; Carcinoma squamous cell; Keratosis actinic; Skin diseases