Zoon''''''''s balanitis is a benign chronic inflammatory lesion of unknown etiology. This article reports the case of a 66-year-old male patient who presented a 2-year history of a erythematous plaque located on the glans penis. The lesion had not been very responsive to conservative topical treatment with corticoid. A significant reduction in the plaque''''''''s size and an improvement in the pruritus was observed with the use of fractional CO2 laser combined with fusidic acid. The treatment was well tolerated and easy to carry out, and improved the patient''''''''s quality of life.

Keywords: PLASMA CELLS, LASER THERAPY, FUSIDIC ACID

Platelet-rich plasma has been proven to be promising in regards to its applicability in dermatology, especially in the healing of chronic ulcers and for soothing signs of aging. The autologous platelet-rich plasma is obtained through blood centrifugation, in a way that its components are separated by density gradient. The final product is a gel rich in growth factors that act in tissue repair, activating fibroblasts and inducing the extracellular matrix remodeling.

Keywords: PLATELET-DERIVED GROWTH FACTOR; PLATELET-RICH PLASMA; TRANSFORMING GROWTH FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTORS; WOUND HEALING

Introduction: Introduction: Androgenic alopecia is the most common type of alopecia. It is characterized by alterations in the hair cycle, leading to progressive follicular miniaturization. Platelet-rich plasma, promotes angiogenesis in the tissue by action of growth factors, which stimulate the hair follicle Objective: To eveluate the hair growth in androgenic alopecia, through cell stimulation performed with the subcutaneous injection of platelet-rich plasma. Methods: Three injections of platelet-rich plasma were performed in 18 patients, at 21-day intervals.The evaluation was performed through comparative clinical photographs, dermoscopy, as well from responses to questionnaires. The Mann-Whitney test and Wilcoxon test were used to analyze the results. Results: For seven women who completed the study, the average improvement was 42.85% (patients) and 35.71% (external observer). For the 9 males, the average improvement was 25.55% (patients) and 18.88% (external observer). In Dermoscopy were observed thickening of hairs, improved local circulation and increased number of follicles. Conclusions: An effective and satisfactory response in androgenic alopecia was verified in relation to the platelet-rich plasma injection technique.

Keywords: ALOPECIA; PLATELET-RICH PLASMA; DERMATOLOGY

Introduction: Male androgenetic alopecia, has high prevalence and causes great discomfort in patients. The platelet-rich plasma generates an environment acts to create a suitable microenvironment for tissue repair and possibly prolongs the anagen phase of the hair follicles.
Objective: To evaluate the safety, efficacy and viability of the PRP use for the treatment of male androgenetic alopecia. Methods: We selected 08 male patients with androgenetic alopecia. Participants had the side of the scalp randomized scalp to receive PRP or placebo. 3 were performed monthly applications.
Results: Patients who received treatment realized some degree of improvement especially as regards the fall. The results were obtained through the analysis dermatoscopic was evaluated as "trichoscale". We observed an increase of anagen hairs, down telogen hairs and vellus wires and increase terminal wires. The results were statistically significant as the reduction of vellus wires and increase of terminals wires.
Conclusions: This study showed a clinical improvement observed for photos as well as positive results documented by analysis "trichoscale". There was statistical significance of data obtained especially after the first month of treatment.

Keywords: ALOPECIA; PLATELET-RICH PLASMA; MEN

Alopecia areata can cause significant psychological problems due to the unpredictable nature of the disease, which results in hair loss. We report the case of a patient presenting alopecia areata of difficult treatment, with satisfactory response after intralesional applications of corticosteroid, but that showed recurrence and atrophy; it was then decided to perform intralesional applications of platelet-rich plasma, with improvement of the condition. The technique showed good results in this isolated case, proving to be a potentially useful therapy in the treatment of alopecia areata.

Keywords: ALOPECIA AREATA; ADRENAL CORTEX HORMONES; PLATELET-RICH PLASMA

Introduction: Acne is a multifactorial disease where inflammatory lesions usually appear as papules, pustules and comedones. It is more common in people aged between 11 and 30 years, and occurs in various body sites where there are high concentrations of pilosebaceous glands. Acne has different classifications and treatments. More recently, platelet growth factors have been used as an alternative therapy for acne scars.
Objective: The present study is aimed at describing a case of nodule-cystic acne and acne scars Grades 1, 2 and 3b treated with platelet rich plasma and highlighting the effectiveness of the treatment.
Methods: Platelet rich plasma was applied for three months in the left side of the face of a patient bearing acne.
Results: In the clinical and photographic evaluations, there was improvement in the skin appearance and quality, less number of lesions and decrease of pain.
Conclusions: The present study has demonstrated the effectiveness of platelet rich plasma as a treatment for acne and resulting scars.

Keywords: PLATELET-RICH PLASMA; ACNE VULGARIS; CICATRIX

Angiosarcoma is a rare and aggressive vascular neoplasia that can occur anywhere in the skin integument, especially in the face and scalp. It has a branched character, and can clinically arise as a macula, papule, plaque or nodule of erythematous hue, with imprecise limits and expansive growth, and diagnosis based on the clinical-pathological correlation. In the present study, the authors report the case of a patient with exuberant cutaneous angiosarcoma on the face, where surgical resection was performed as the first therapeutic option.

Keywords: Dermatology; Hemangiosarcoma; Sarcoma; Vascular neoplasms

Vascular anomalies correspond to a broad spectrum of changes that fall into two main groups: 1) vascular tumors, which represent proliferative lesions, and 2) vascular malformations, caused by ectasia in vessels, whether capillary, venous or lymphatic.This article reviews the main vascular anomalies observed in dermatological practice, their main classifications and available treatments, focusing on the use of lasers and intense pulsed light to lighten cutaneous vascular lesions, especially those resulting from malformations.

Keywords: vascular Malformations; Hemangioma; Vascular neoplasms; Laser therapy; Intense pulsed light therapy; Dermatology

Angiokeratomas are vascular malformations constituted by telangiectasia of preexisting vessels. They are not classified as angiomas. It is the rarest variant of angiokeratomas, with few cases in the literature. The mechanism of development of these lesions has not yet been fully elucidated. Small lesions can be treated with electrosurgery, curettage, or cryosurgery. Larger lesions require deep surgical excision, and depending on the size and depht of the lesion, direct closure, flap, or grafting. CO2 or argon laser are considered other treatment options. In this case report we describe a classic case of circumscribed angiokeratoma, with onset at birth, and progressive growth.

Keywords: Ambulatory surgical procedures; Dermatology; Vascular malformations

Cryosurgery is a technique widely known and used among dermatologists. Intralesional application is already used to treat keloids and has the advantage of restricting the zone of action of low temperatures of liquid nitrogen. The use of contact cryosurgery in vascular lesions is well reported in the literature, but there are no intralesional technique publications on these types of lesions. Here, we report two cases, one of port-wine stain hamartomas in a 61-year-old patient and another of a cherry angioma in a 70-year-old patient, safely and satisfactorily treated with intralesional cryosurgery.

Keywords: Cryosurgery; Cryotherapy; Hamartoma; Hemangioma; Vascular malformations

O queratoacantoma (QA), apesar de frequente na prática diária, é um tumor que gera questionamentos. O aspecto mais intrigante associa-se à sua posição no limite entre malignidade e benignidade. A abordagem do tumor, bem como sua classificação, é controversa. Na definição da conduta, é importante levar em conta o potencial de transformação para carcinoma espinocelular. Desse modo, a excisão cirúrgica é a terapia de escolha, sempre que possível. Algumas situações merecem atenção adicional, como a imunossupressão associada. Neste artigo, relatamos um caso de QA gigante em um paciente com síndrome da imunodeficiência adquirida tratado com cirurgia micrográfica de Mohs.

Keywords: Ceratoacantoma; Retalhos Cirúrgicos; Neoplasias Nasais; Neoplasias Cutâneas; Cirurgia de Mohs; Síndrome de Imunodeficiência Adquirida; HIV; Imunossupressão

Sarcomas são neoplasias mesenquimais malignas, raras, que acometem, principalmente, crianças e adolescentes. O rabdomiossarcoma, subtipo oriundo da musculatura esquelética, é condição incomum em adultos, acometendo sítios de localização não habitual, crescimento rápido e de difícil tratamento. Apresenta-se caso de adulto jovem com nodulação em lóbulo auricular esquerdo, cuja análise histopatológica e imuno-histoquímica confirmou tratar-se de rabdomiossarcoma alveolar, o qual foi conduzido em conjunto com a Oncologia.

Keywords: Rabdomiossarcoma Alveolar; Miogenina; Desmina; Excisão de Linfonodo

A Covid-19, doença causadora de síndrome gripal e insuficiência respiratória aguda, vem demonstrando provocar danos a diversos outros órgãos e sistemas. Várias manifestações dermatológicas já foram descritas. Relatamos um quadro de alopecia areata (AA) desencadeada possivelmente pela Covid-19 em paciente que, apesar de ter seu RT-PCR para SARS-CoV-2 negativo, apresentou IgM reagente e sintomatologia clássica relacionada à doença. Acreditamos que a Covid-19 possa ter desencadeado resposta imunológica autoimune, com a consequente produção de interferons, que levou ao quadro de AA.

Keywords: Alopecia em áreas; Autoimunidade; Coronavirus

The present study is a scientometric analysis aiming to verify the scientific production about radiofrequency in facial wrinkles. The databases used were the Web of Science and Pubmed. We searched the literature for all articles with the terms "Radiofrequency", "Facial", and "Wrinkle" in the title, abstract, or keywords. For each study, we analyzed the following scientometric indicators: publication number per year, name of the journal, authors, impact factor, country of publication, and type of study.

Keywords: Aging; Aesthetic equipment; Plasma

Intravascular endothelial hyperplasia, or Masson’s tumor, is a benign vascular lesion with no well-defined pathogenesis. The response to vascular damage is believed to be one of the main reasons for its development. It is a typically painless injury, solitary, with slow evolution. This report aims to describe a case of Masson’s tumor in an unusual place, the hallux nail matrix, and discuss its main characteristics.

Keywords: Hyperplasia; Hallux; Endothelium, Vascular.