Onychomatricomas are rare benign tumors originating from the nail matrix and underlying stroma. They are usually asymptomatic and slow growing, affecting both middle-aged men and women, and more frequently involve the digits of the hands. Key clinical features for diagnosis are: yellowish longitudinal band of variable width, splinter hemorrhages, longitudinal grooves associated with the transverse overcurvature and fingerlike projections emerging from the nail matrix. The authors report three cases of this tumor affecting toes, emphasizing main clinical aspects, dermoscopic findings, and surgical treatment.

Keywords: NAILS; NAILS, MALFORMED; NEOPLASMS.

The authors describe the case of a 75-year-old female patient, bearing a single asymptomatic, nodular lesion of fibroelastic consistency for three years, located on the left hallux. Following surgical excision of the lesion, the pathological examination and immunohistochemistry revealed a superficial acral fibromyxoma. This type of lesion was first described in 2001 and today there are approximately 100 cases in the literature. It is a benign mesenchymal tumor of slow growth, with a predilection for ungual and peri-ungual regions. There are no reports of malignant transformation and recurrence has been associated with incomplete resection.

Keywords: FIBROMA; NEOPLASM; NAIL DISEASES.

Squamous cell carcinoma is related to exposure to UVB radiation and the presence of chronic cutaneous lesions. Folliculitis decalvans is a cicatricial alopecia that develops with the inflammation of the scalp. In the medical literature, the association between folliculitis decalvans and squamous cell carcinoma is rare, a factor motivating this report. A 66-year-old male patient, bearer of folliculitis decalvans since childhood, complained of progressive growth of lesions in the alopecia area. The biopsy confirmed squamous cell carcinoma. This case report covers the concept of "Marjolin ulcer" for including folliculitis decalvans as inflammatory lesion precursor of squamous cell carcinoma.

Keywords: ALOPECIA; CARCINOMA, SQUAMOUS CELL; FOLLICULITIS

Melanonychia corresponds to color patterns in the nail plate, ranging from brown to black. It is a diagnostic challenge due to the fact it has several differential diagnoses, including benign and malignant entities. There are no reports of pigmented fibroma of the nail matrix causing striata (or longitudinal) melanonychia. In light of this fact, the authors report a case of melanonychia striata secondary to pigmented fibroma of the nail, with clinical examination and dermoscopic findings suggestive of nodular melanoma.

Keywords: NAILS; MALFORMED NAILS; NEOPLASMS; FIBROMA

Introduction: Glomus tumor is a benign and rare neoplasm that appears as solitary and painful nodule, mainly subungual. It presents characteristic clinical manifestations such as paroxysmal pain and sensitivity to local pressure and to cold.
Objective: To conduct a clinical epidemiological survey of glomus tumors diagnosed in a reference unit in 16 years.
Methods: Retrospective study assessing clinical and epidemiological data of 15 patients with glomus tumor confirmed by histopathological report from 2000 to 2016. Data on age, gender, tumor location, associated symptoms, duration of symptoms until diagnosis, clinical presentation, histological type and recurrence after surgery were analysed.
Results: Fifteen cases were diagnosed, 11 in women (73.3%) and four in men (26.7%). Mean age was 63 years. The most frequent location was the subungual region. Mean duration of symptoms until diagnosis was 8 years.
Conclusions: In this study, the number of cases of glomus tumor fluctuated throughout these 16 years, with a mean of 0.9 cases/year. A higher prevalence in women over 60 years, subungual region location and solid glomus histologic subtype was observed.

Keywords: GLOMUS TUMOR; NAIL DISEASES; NEOPLASMS

The Merkel cell carcinoma is a rare and highly aggressive neuroendocrine skin tumor. The purpose of this paper is to warn of the possibility of this diagnosis, usually not considered as an initial hypothesis in cutaneous neoplasias. The authors describe two cases of elderly female patients with complaints of a single erythematous nodule on the face. The diagnoses of basal cell carcinoma and amelanotic melanoma were considered. The presence of telangiectasias was evident at dermoscopy. The incisional biopsy's histology evidenced Merkel cell carcinomas. This neoplasia typically occurs in Caucasian patients with over 65 years of age, emerging as an erythematous-purplish nodule of rapid growth, with immunohistochemistry being essential for the diagnosis.

Keywords: SKIN NEOPLASMS; CARCINOMA, MERKEL CELL; NEUROENDOCRINE TUMORS; IMMUNOHISTOCHEMISTRY

Subungual squamous cell carcinoma is a rare condition, and its diagnosis is often late. The clinical presentation is atypical and simulates other benign conditions, such as verruca vulgaris, onychomycosis and trauma-induced nail dystrophy. Although it is an unusual entity, we should be attentive to its early diagnosis, considering the biopsy in the chronic nail lesions refractory to treatments. We present five cases of subungual squamous cell carcinoma, in which pain was the most prevalent symptom, and their possible association with trauma and HPV infection should be considered.

Keywords: CARCINOMA, SQUAMOUS CELL; NAILS; NAIL DISEASES

Lichen planopilaris is a rare disorder that belongs to the primary scarring alopecia type. The present study describes the case of a female patient bearing desquamative erythematous plaques and follicular plugs bilaterally in the frontoparietal region, associated with positive pull test. The biopsy's result was consistent with lichen planopilaris and the patient was treated with prednisone associated with clobetasol, with regrowth of the hair in the affected area. The treatment of this pathology is a challenge due to the lack of data on efficacy of therapies and constant recurrence. The picture is irreversible if not treated early. This paper describes a classic case of a case of lichen planopilaris with good therapeutic response, highlighting the importance of early diagnosis, due to the fact that most cicatricial alopecias do not produce scarring in their initial stage and should for this reason be managed as an emergency in trichology.

Keywords: ALOPECIA; EARLY DIAGNOSIS; LICHEN PLANUS