Hidradenitis suppurativa is a chronic inflammatory disease resulting from follicular obstruction. This recurrent condition leads to the formation of fistulas and scars, which affect a patient's quality of life. The literature offers multiple therapeutic modalities, such as topical and oral antibiotics, isotretinoin, dapsone, TNF-α inhibitors, finasteride, conventional surgical therapies, and lasers (CO₂, Nd:Yag). The present article provides a review of these treatments and their indications, according to the stages of Hurley, which provides the dermatologist with a greater command of different techniques, thus leading to a more adequate treatment of patients.

Keywords: HIDRADENITIS SUPPURATIVA; THERAPEUTIC; LASER THERAPY.

Introduction: Hidradenitis is a chronic inflammatory disease that has a negative impact on the patient's quality of life but which has few effective therapeutic options. Currently, the use of laser technology has been standing out as a treatment. Objective: To evaluate the use of 1,340nm ND:YAP laser (Neodimiun:Ytrium Aluminum Perovskite) to treat hidradenitis. Methods: Performing 4 1,340nm ND:YAP laser sessions in 3 patients bearing hidradenitis. Results: All patients had a clinically and histologically evidenced reduction of inflammatory lesions. Conclusions: In the present study, the 1,340nm ND:YAP laser was effective in the treatment of hidradenitis, and can potentially become a new therapeutic option.

Keywords: HIDRADENITIS; LASERS; LASER THERAPY

Hidradenitis suppurativa is a chronic inflammatory, recurrent and debilitating skin disease. Its etiopathogenesis involves follicular occlusion and genetic, environmental and immunological factors. Diagnosis is predominantly clinical, and the therapeutic approach is a major challenge due to its impact on the patient's quality of life. The surgical option is the most indicated in severe cases, nevertheless there is no consensus on the ideal treatment, as outcomes are diverse, and the aesthetic aspect after the procedure is generally unfavorable. This article was aimed at reporting a surgical option with primary wound closure, whose aesthetic result was superior to those derived from traditional techniques.

Keywords: HIDRADENITIS SUPPURATIVA; HIDRADENITIS; DERMATOLOGIC SURGICAL PROCEDURES; DERMATOLOGY; THERAPEUTICS

Introduction: Melasma is a pigmentation disorder that mainly affects women of childbearing age with high phototypes. Polypodium leucotomos has antioxidant, photoprotective and immuno-modulatory activity, and can be considered as an adjunctive treatment for melasma.
Objective: To evaluate the efficacy, in relation to quality of life and objective improvement, of the use of Polypodium leucotomos in the treatment of melasma.
Methods: Prospective and individualized study. Nine volunteers with melasma were submitted to treatment with Polypodium leucotomos for 45 days. MELASQoL, DLQI and MASI scores were calculated at the beginning (D0) and 45 days after (D45). Analysis of variance ANOVA with Tukey post-test for comparison be-tween D0 and D45 (p <0.05).
Results: All patients were females, mean age of 37.18 ± 6.78 years. Family history of melasma in 55.6%; 88.9% with unprotected photoexposure and use of estrogen. After 45 days of treatment with Polypodium leucotomos there was a significant reduction of ME-LASQoL and DLQI (p <0.05) and improvement of MASI in 55.6% of the patients.
Conclusions: There was improvement of MASI in 55.6% of patients after 45 days of treatment. In spite of the slight improvement in MASI, there was a reflex in the improvement of quality of life scores (DLQI and MELASQoL).

Keywords: MELANOSIS; POLYPODIUM; QUALITY OF LIFE; INDICATORS OF QUALITY OF LIFE

INTRODUCTION: Hidradenitis supurativa (HS) is a chronic skin disease whose mechanism is not yet fully understood. It has a direct impact on the quality of life of affected patients, but there is no well-established therapy for its treatment.
OBJECTIVE: To assess the quality of life of patients diagnosed with HS on adalimumab using the Dermatology Life Quality Index (DLQI) questionnaire.
METHODS: Information was collected from patients with HS on adalimumab and standard DLQI questionnaires were applied before the beginning of treatment and at least 12 weeks after.
RESULTS: Of the three patients included, two presented decreased DLQI. Of these two, one showed significant improvement after treatment with adalimumab. The third patient showed worsening of this index.
CONCLUSIONS: The impact of hidradenitis supurativa on the quality of life of affected patients is significant and is related to factors other than adequate therapy. Life habits such as smoking and alcoholism, as well as the presence of other comorbidities, probably impact these indices. Affected patients should be assessed globally to determine the actual impact on the quality of life related to the disease in question. Thus, we suggest further studies with a larger number of patients.

Keywords: Hidradenitis suppurativa; Quality of life; Indicators of quality of life

Dowling-Degos disease (DDD) is a rare genodermatosis. Progressive reticular hyperpigmentation of flexural areas mainly characterizes the disease, which may be associated with a large spectrum of benign lesions and cutaneous neoplasms. It may cause psychosocial impairment due to the deformity caused by the lesions with significant aesthetic damage. We present two cases of male patients with hyperchromic macules, multiple comedones, epidermal cysts, cribriform scars on the face, cervical region, dorsum, anterior thorax, armpits, genital region, and disfiguring tumors, characteristic of DDD.

Keywords: Carcinoma; Genetics; Hidradenitis; Hidradenitis Suppurativa; Skin Pigmentation

O queratoacantoma (QA), apesar de frequente na prática diária, é um tumor que gera questionamentos. O aspecto mais intrigante associa-se à sua posição no limite entre malignidade e benignidade. A abordagem do tumor, bem como sua classificação, é controversa. Na definição da conduta, é importante levar em conta o potencial de transformação para carcinoma espinocelular. Desse modo, a excisão cirúrgica é a terapia de escolha, sempre que possível. Algumas situações merecem atenção adicional, como a imunossupressão associada. Neste artigo, relatamos um caso de QA gigante em um paciente com síndrome da imunodeficiência adquirida tratado com cirurgia micrográfica de Mohs.

Keywords: Ceratoacantoma; Retalhos Cirúrgicos; Neoplasias Nasais; Neoplasias Cutâneas; Cirurgia de Mohs; Síndrome de Imunodeficiência Adquirida; HIV; Imunossupressão

Sarcomas são neoplasias mesenquimais malignas, raras, que acometem, principalmente, crianças e adolescentes. O rabdomiossarcoma, subtipo oriundo da musculatura esquelética, é condição incomum em adultos, acometendo sítios de localização não habitual, crescimento rápido e de difícil tratamento. Apresenta-se caso de adulto jovem com nodulação em lóbulo auricular esquerdo, cuja análise histopatológica e imuno-histoquímica confirmou tratar-se de rabdomiossarcoma alveolar, o qual foi conduzido em conjunto com a Oncologia.

Keywords: Rabdomiossarcoma Alveolar; Miogenina; Desmina; Excisão de Linfonodo

INTRODUCTION: Hidradenitis suppurativa (HS) is an inflamatory, chronic, recurrent, and debilitating condition. There is a lack of consensus about its treatment.
OBJECTIVE: We conducted a review of the national and international literature, searching for articles that addressed the use of botulinum toxin in HS, in addition to describing the doses and techniques used.
METHODS: A bibliographic search was performed in LILACS, Medline, and SciELO.
RESULTS: Botulinum toxin can be an effective therapy in patients with HS, especially in cases of concomitant hyperhidrosis and traditional therapies fail. It offers the possibility of conducting treatment with minimal adverse events, reproducible over time without loss of effectiveness, in addition to reducing pain.
CONCLUSIONS: Patients will likely need more than one treatment over time, as the lesions tend to recur after 6 to 10 months. The technique used has been the standard for hyperhidrosis. Further research is needed to understand its role in the management of HS, including the ideal dosage and frequency of administration.

Keywords: Hidradenitis suppurativa; Hidradenitis; Botulinum toxins; Botulinum toxins, type A

INTRODUCTION: Hidradenitis Suppurativa is a chronic inflamatory and relapsing disease. High levels of recurrence can persist even after wide local excision.
OBJECTIVE: Identify the main risk factors for postoperative complications of Hidradentis Suppurativa.
METHODS: We included journal articles with data from Google, Pubmed, Lilacs, and Scielo, in Portuguese and English, from 2000 to 2021.
RESULTS: The main risk factors that influence postoperative outcomes are related to surgical technique, disease severity, comorbidities, and adjuvant clinical therapy.

Keywords: Hidradenitis suppurativa; Risk factors; Postoperative complications