Surg Cosmet Dermatol. 2011;3(1):12-16
Introduction: Some foods can have therapeutic value in the treatment of photoaging.
Objective: To clinically evaluate the efficacy of a nutritional supplement in the improvement of photoaging signs and correlate with an in vitro study.
Methods: A nutritional supplement was evaluated clinically and in vitro, with a culture of fibroblasts. Patients with clinical signs of photoaging (n = 48) were studied while using a nutritional supplement, with clinical and instrumental (cutometry) evaluations at 56, 84 and 112 days.
Results: There was progressive and significant improvement (p < 0.05) in the elasticity, firmness, fine lines and general appearance of the skin.The fibroblast cultures indicated a significant rate of collagen synthesis when compared to the control culture after 48 hours of incubation.
Discussion: The oral use of some vitamins and natural compounds has a therapeutic effect on the signs of photoaging.This study has demonstrated that a combination of linseed oil, lycopene, carotenoids, vitamin E, zinc and selenium possibly improve the signs of aging not only through antioxidant and anti-inflammatory mechanisms, but also by increasing collagen production.
Conclusions: Nutritional supplements are useful in the care of photoaged skin.
Keywords: FIBROBLASTS, SKIN AGING, ANTIOXIDANTS