Keloids were first described several centuries ago, however their handling and treatment are still often inadequate. A number of treatments are available, such as intralesional corticotherapy and compressive therapy. The case of a 24-year-old female patient with a 5 year history of keloids in the ear lobules, with recurrence after treatment, is reported. She experienced a full regression of the lesions (for 2 years) after surgical reduction followed by intralesional bleomycin injections. Bleomycin is emerging as a therapeutic option with few side effects and lasting results for keloids that are unresponsive to conventional treatments.

Keywords: BLEOMYCIN, CICATRIX, HYPERTROPHIC, KELOID

Cryosurgery is an established technique for treating keloids. The development of intralesional cryosurgery has been an important advance in that technique. In addition to producing better results in large and refractory keloids, intralesional cryosurgery presents a lower rate of complications. The authors present a new low-cost device for use in intralesional cryosurgery that allows easy handling in practically all body areas.

Keywords: KELOID, CRYOSURGERY, SURGICAL EQUIPMENT

A tattoo results from the introduction of pigments into the skin or mucous membranes. Pigments are chemical substances that behave like optical markers. Their visibility (through epithelial transparency) is undeniable proof that cutaneous perfusion with micro-perforations is an effective procedure. This method was used to infuse Bleomycin sulfate in two patients bearing keloid lesions, employing the same equipment and components used by professional tattoo artists, with adaptations for dermatological use, and strictly observing aseptical and rational requirements.

Keywords: SURGICAL EQUIPMENT, THERAPEUTICS, KELOID, BLEOMYCIN

Keloids and hypertrophic scars result from abnormal wound healing with excessive growth of fibrous tissue. Despite the high incidence in the population, the high rates of relapse and the significant psychosocial impairment, treatment remains a challenge for dermatologists. The objective of this study was to review literature on clinical, etiological and therapeutical aspects of keloids and hypertrophic scars, emphasizing its therapy with bleomycin, demonstrating its effective and safe use. The search was conducted in Scopus and MEDLINE databases, for the period from 1995 to 2016, using the key words: queloide/keloid; cicatriz hipertrófica/cicatrix, hypertrophic; and bleomicina/bleomycin.

Keywords: KELOID; CICATRIX, HYPERTROPHIC; BLEOMYCIN

Viral warts are one of the most prevalent dermatoses. The clinical picture varies from a single lesion with spontaneous cure to multiple recalcitrant lesions. Bleomycin sulfate is a cytotoxic action drug approved for the chemotherapeutic treatment of some malignancies. There are a number of studies that have been carried out during the last 45 years demonstrating its usefulness in dermatology, especially in intralesional therapy for viral warts, meaning it is an excellent option for lesions in difficult-to-handle topographies and for cases that do not respond to other approaches.

Keywords: Bleomycin; Drug therapy; Viral wart

The tissue processing in Mohs surgery aims at histological slides that allow the analysis of 100% of the surgical margins. The embedding tissue is a critical step and prone to errors. As there is no standardization when mounting the blocks, there may be unevenness in the different samples cutting surfaces, leading to the need for continuous adjustments on the X-Y axis inside the cryostat, slowing down the process. A device was developed to solve this problem, minimizing any blocks inclination, keeping the surgical margins parallel in all samples, accelerating the process, and maintaining the histological slides high quality.

Keywords: Mohs micrographic surgery; Laboratory equipment; Histology; Tissue embedding; Innovation

O queratoacantoma (QA), apesar de frequente na prática diária, é um tumor que gera questionamentos. O aspecto mais intrigante associa-se à sua posição no limite entre malignidade e benignidade. A abordagem do tumor, bem como sua classificação, é controversa. Na definição da conduta, é importante levar em conta o potencial de transformação para carcinoma espinocelular. Desse modo, a excisão cirúrgica é a terapia de escolha, sempre que possível. Algumas situações merecem atenção adicional, como a imunossupressão associada. Neste artigo, relatamos um caso de QA gigante em um paciente com síndrome da imunodeficiência adquirida tratado com cirurgia micrográfica de Mohs.

Keywords: Ceratoacantoma; Retalhos Cirúrgicos; Neoplasias Nasais; Neoplasias Cutâneas; Cirurgia de Mohs; Síndrome de Imunodeficiência Adquirida; HIV; Imunossupressão

The present study is a scientometric analysis aiming to verify the scientific production about radiofrequency in facial wrinkles. The databases used were the Web of Science and Pubmed. We searched the literature for all articles with the terms "Radiofrequency", "Facial", and "Wrinkle" in the title, abstract, or keywords. For each study, we analyzed the following scientometric indicators: publication number per year, name of the journal, authors, impact factor, country of publication, and type of study.

Keywords: Aging; Aesthetic equipment; Plasma

INTRODUCTION: High-intensity focused electromagnetic field treatment (HIFEM) uses low-frequency electromagnetic waves to induce supramaximal muscle contractions, causing muscle hypertrophy and reducing fat.
OBJECTIVE: To evaluate the effects of a HIFEM treatment for the improvement of cellulite on the buttocks.
METHODS: Thirty patients were divided into two groups that received eight or 12 HIFEM sessions on the buttocks for six weeks. We assessed the improvement in cellulite and the buttocks' global appearance through the Cellulite Severity Scale (CSS), the Global Aesthetic Improvement Scale (GAIS), and a satisfaction questionnaire. Changes in body composition were evaluated through bioimpedance and hip circumference measurements.
RESULTS: Patients from both groups improved the global appearance of their buttocks. Cellulite lesions of some patients improved, but for most patients, the improvement wasn’t great enough to change the grade on the Cellulite Severity Scale. Patient satisfaction was high and adverse events were few, minor, and transitory.
CONCLUSION: The effects of HIFEM on cellulite are subtle, as this treatment modality cannot address the fibrous septa that cause the depressed lesions of cellulite. Nevertheless, HIFEM procedures can improve the buttocks’ global appearance, enhancing the patients’ subjective perception of their cellulite.

Keywords: Cellulite; Aesthetic equipment; Electromagnetic fields

Eyebrow ptosis presents a significant challenge for cosmetic professionals. Minimally invasive procedures can improve eyebrow positioning; however, a thorough understanding of its varied etiologies is essential. The primary causes include skin laxity, muscular dysfunction, and tissue deflation, with the latter subdivided into frontal, temporal, and superciliary deflation. A precise diagnosis allows for the appropriate indication of microfocused ultrasound, botulinum toxin, biostimulators, and hyaluronic acid-based fillers, either as standalone treatments or in combination. At the end of this review, a treatment algorithm for eyebrow ptosis is proposed.

Keywords: Dermal Fillers; Botulinum Toxins; Eyebrows; Aesthetic Equipment.