Introdução:There is no standardized approach to immediate post-procedure care for epidermal ablation; the conscientious choice of products can provide greater comfort to the patient, reduced risks and complications, and shorter recovery times. Objective: To analyze the safety and effectiveness of silicone spray in tissular restoration after two epidermal ablation procedures – fractional ablative 2,790 nm YSGG laser and dermabrasion. Methods: Patients with photoaging or acne scars (n = 20) applied silicone spray on one side of the face and liquid Vaseline (control) on the other side of the face after the procedures.Transepidermal loss of water was measured in all patients. Results: Erythema and burning sensation were the most common findings, and were significantly more frequent in the areas where Vaseline was applied. Conclusions: Silicone spray is safe and effective for use after epidermal ablative procedures, and is significantly superior to Vaseline in controlling burning sensations and erythema

Keywords: SILICONES, WOUND HEALING, DERMABRASION, LASER THERAPY

Since ancient times, humans have had an interest in improving their body contour. Liquid silicone has been used for this purpose, in order to improve deformities. The authors present a case of a female patient with paralysis in the right lower limb, who underwent improper injections of a large volume of injectable silicone in the affected limb aimed at correcting its contour. Ten years later, the patient developed local complications linked to the silicone injections - localized scleroderma lesions and superficial lipomatous nevus with progressive growth in the affected limb - and clinical and laboratory pictures of rheumatoid arthritis. Injectable liquid silicone should be contraindicated as a substance for implants.

Keywords: POSTOPERATIVE COMPLICATIONS; SILICONES; SKIN NEOPLASMS

Factitious panniculitis can be triggered by subcutaneous injections of substances linked to esthetic procedures. A case diagnosed and treated as chronic erythema nodosum manifested nodule five years later, with the anatomopathological study suggesting atypical lipomatous tumor. After resection of the lesion, histology showed steatonecrosis, compatible with lobular panniculitis. Magnetic resonance imaging examination revealed the presence of a liquid substance in the gluteal region, favoring the diagnostic suspicion of factitious panniculitis. The patient admitted to having undergone silicone injection in this region in the past, with additional findings arising from the histological review confirming this hypothesis. The late complication linked to injections of cutaneous filling material motivated the present study.

Keywords: Erythema chronicum migrans; Panniculitis; Silicones

Scar formation is the natural healing response of the skin to reestablish dermal integrity after an injury. Besides being unsightly, the scars can also be hypertrophic or keloids, which makes treatment challenging and many times unsatisfactory. Ethnicity and site of the lesion have an important role in the formation of scar types, but it is not always possible to predict the final result. The use of topical silicone has been an option for scar management and the target of many publications over the years. It is believed that its early use can prevent the development of abnormal scars and treat existing scars.

Keywords: Scars, prevention & control; Silicone gels; Treatment

Introduction: Silicone dressings and Triamcinolone injections are known to improve keloids and hypertrophic scars size, erythema, flexibility, and symptoms such as pain and itching. These treatments are non-invasive, inexpensive, and widely used as first or second-line therapy; however, studies comparing them are still lacking.
Objective: To compare silicone dressings, triamcinolone injections, and a combination group, to treat hypertrophic scars, at the same anatomical area, caused by the same mechanism of injury.
Materials and methods: In a prospective study, 12 patients with median-sternotomy scars were randomized into 3 groups (n=4 patients each): group 1, monthly triamcinolone injections; group 2, a combination of silicone dressings and triamcinolone injections; and group 3, silicone dressings. Patients were evaluated in monthly clinical appointments using the Vancouver Scale and the durometer. Immunohistochemistry and confocal microscopy for collagen types I and VI were performed in scar samples. The groups were compared using Kruskal-Wallis and Friedman tests, with p<0,05 indicating significance.
Results: The three treatments were effective in reducing the Vancouver scores. A difference between the three groups was observed at time 2 when triamcinolone was less effective. Group 2 showed an improvement on pigmentation (p = 0,042). Collagens types I and VI presented increased fluorescence throughout the superficial and deep dermis in untreated lesions, which decreased after the treatment. Although the number of patients is limited, this is the first prospective study addressing some of the major bias in scars treatment.

Keywords: Scar; Keloid; Silicone gel; Triamcinolone

O queratoacantoma (QA), apesar de frequente na prática diária, é um tumor que gera questionamentos. O aspecto mais intrigante associa-se à sua posição no limite entre malignidade e benignidade. A abordagem do tumor, bem como sua classificação, é controversa. Na definição da conduta, é importante levar em conta o potencial de transformação para carcinoma espinocelular. Desse modo, a excisão cirúrgica é a terapia de escolha, sempre que possível. Algumas situações merecem atenção adicional, como a imunossupressão associada. Neste artigo, relatamos um caso de QA gigante em um paciente com síndrome da imunodeficiência adquirida tratado com cirurgia micrográfica de Mohs.

Keywords: Ceratoacantoma; Retalhos Cirúrgicos; Neoplasias Nasais; Neoplasias Cutâneas; Cirurgia de Mohs; Síndrome de Imunodeficiência Adquirida; HIV; Imunossupressão

Sarcomas são neoplasias mesenquimais malignas, raras, que acometem, principalmente, crianças e adolescentes. O rabdomiossarcoma, subtipo oriundo da musculatura esquelética, é condição incomum em adultos, acometendo sítios de localização não habitual, crescimento rápido e de difícil tratamento. Apresenta-se caso de adulto jovem com nodulação em lóbulo auricular esquerdo, cuja análise histopatológica e imuno-histoquímica confirmou tratar-se de rabdomiossarcoma alveolar, o qual foi conduzido em conjunto com a Oncologia.

Keywords: Rabdomiossarcoma Alveolar; Miogenina; Desmina; Excisão de Linfonodo

A 76-year-old woman presented with facial edema and nodules in the front glabellar region and nasal dorsum that clinically resembled leonine facies. A facial ultrasound showed deposits of permanent facial filler with a "snowstorm" aspect characteristic of silicone oil, and an anatomopathological examination suggested a granulomatous reaction to the exogenous substance. Permanent fillers, such as silicone, behave like foreign bodies and cause a chronic granulomatous reaction. Although dermal fillers have been increasingly used, there is still no consensus on the management of their complications. In the present case, a good response to dapsone was observed.

Keywords: Silicones; Dermal Fillers; Granulomatous Disease, Chronic; Foreign-Body Reaction.

INTRODUCTION: Multiple treatments that promise to prevent or treat skin aging act on cellular functions, reducing skin aggression mechanisms, or even on the loss of skin barrier properties. Silicone adhesives appear to have a positive effect on barrier function and modulation of inflammation, but their clinical effects have not yet been documented.
OBJECTIVE: To evaluate the effectiveness of silicone adhesives in reducing the signs of periorbital aging.
METHODS: 33 patients between 35 and 55 years old with a clinical diagnosis of aging in the periorbital region were selected; Of these, 23 underwent hydration measurements (corneometry) and skin relief (prophylometry). All participants used the patches daily for a period of 30 days.
RESULTS: After four weeks of use, the application of silicone adhesives provided a significant improvement in hydration levels and the skins microrelief, making it smoother. The clinical and subjective evaluation corroborated these findings, and also showed a relevant improvement in clinical and subjective parameters such as hydration, softness, texture, and expression lines.
CONCLUSION: The continued use of silicone adhesives demonstrated a beneficial effect on some signs of aging, possibly related to improved hydration and modulation of inflammation.

Keywords: Skin Aging; Epidermis; Silicone Elastomers.