Burns are still the cause of a great portion of injuries and deaths triggered by external factors in Brazil. Also, it is intensely linked to absenteeism, and functional and aesthetic sequelae, especially in the male population. The assessment of burns should take into account their depth and location, involvement of the upper airways and causative agent. In cases where the treatment is carried out in an outpatient setting, after adequate washing of the lesions, 1% silver sulfadiazine cream is still the topical antimicrobial of choice, in addition to tetanus prophylaxis. Aimed at avoiding possible limitations of motion and social interaction, the prevention of hypertrophic scars and keloids is very important.

Keywords: burns; silver sulfadiazine; cicatrix; keloid

Introduction: Signs of aging usually arise more intensely on the face, neck, and hands, in the form of considerable loss of volume, which is a common indicator of aging.
Objective: To compare the duration, and adverse effects of two types of subcutaneous fillers in the treatment of the volumetric aging of hands.
Methods: Group A: four patients who used the same amount of the products in both hands; Group B: four patients who used greater amounts of calcium hydroxyapatite in one of the hands and Group C: four patients who used greater amounts of hyaluronic acid also in one of the hands. The patients were evaluated through changes in a validated scale for hand aging, recorded by digital photographs before and 1,3,6,9,12,15 and 18 months after the procedure.
Results: In Group A the patients had the same duration for both fillers; in Group B patients treated with hydroxyapatite calcium had longer duration; in Group C, the patients treated with hyaluronic acid presented longer duration. Adverse effects were more frequent with the use of calcium hydroxyapatite.
Conclusions: It can be concluded that the filler duration is proportional to the volume injected for both fillers, and that hyaluronic acid is safer for the treatment of this cosmetic irregularity.

Keywords: hyaluronic acid; hand dermatoses; rejuvenation

Introduction: Microneedling is a technique aiming at stimulating the production of collagen as well as serving as drug delivery. Copaiba oil has healing and anti-inflammatory effects that have already been demonstrated in several animal models.
Objective: To evaluate the effect of copaiba oil associated with microneedle removal on the skin of rats.
Methods: Thirty rats were distributed in six groups of five animals each, subsequently undergoing: isolated microneedling, microneedling associated to mineral oil, and microneedling associated with copaiba oil. Biopsies were carried out in all animals at 14 and 30 days after the procedure. The parameters evaluated were: presence of collagen, fibroblasts and vessels, according to the following ratings: absence (0), mild (1), moderated (2) or intense (3).
Results: There was a statistically significant difference between the groups regarding the production of collagen at 14 days (p = 0.0091) and 30 days (p = 0.0357); and fibroblasts at 30 days (p = 0.0357). the group that used microneedling and copaiba oil, presented, after 30 days, a greater production of collagen and fibroblasts.
Conclusions: Copaiba oil associated with microneedling was capable of stimulating a greater production of collagen and fibroblasts in the skin of rats.

Keywords: dermatology; plants, medicinal; wound healing; collagen

Introduction: Hyaluronic acid-based soft tissue fillers are considered one of the treatment options for hands rejuvenation.
Objective: To evaluate the efficacy a range of soft hyaluronic acid (HA) gels in women with loss of adipose tissue and dermal reabsorption as a sign of aging hands.
Methods: Fifteen subjects received treatment with two firmer HA gels combined with the softest gel of the range (group 1). Fifteen subjects received the two firmer HA gels only (group 2). Efficacy and safety assessments were performed at month one, three and six. Patient satisfaction and self-assessment questionnaires were applied.
Results: Most subjects were Caucasian (Fitzpatrick skin type III and IV) with a mean age of 56.6 years. Six months after treatment, all the subjects in Group 1 and 93% in Group 2 had clinical improvement; and 90% of the subjects in both groups presented global aesthetic improvement. Mild pain was reported in both groups. All related adverse events were mild or moderate.
Conclusions: Both treatments were effective and safe, and improvement was seen for up to six months after treatment. Subjects reported high satisfaction with both treatments up to the end of study.

Keywords: hand; rejuvenation; hyaluronic acid; skin aging

Introduction: Microneedling, also known as percutaneous collagen induction therapy, is a safe and effective procedure, mostly used for rejuvenation, treatment of scars, melasma, alopecia, and other conditions, as well as for drug delivery. Despite the safety and benefits of this technique, the control of pain during the procedure is its major limiting factor.
Objectives: To assess whether the drug delivery system for topical anesthesia immediately before a microneedling session is capable of reducing the pain.
Methods: A split-face pilot study was carried out with nine consecutive cases of microneedling that had been indicated for the treatment of acne scars, rejuvenation and collagen induction. All patients underwent cleansing of the skin followed by the application of topical anesthetics on the entire face, and drug delivery with a 0.5mm roller only on the left hand side of the face. Next, all anesthetics were removed and microneedling with a 1.0mm roller was performed on both sides of the face
Results: There was a significant reduction of the pain on the left hand side of the face, where the drug delivery was carried out (p <0.01), with a mean value of 3.33 (± 1.49) on the Visual Analogue Scale as compared to the right hand side, which yielded a mean value of 5.22 (± 1.74).
Conclusion: The topical anesthetic drug delivery technique was effective and successful in reducing the pain during microneedling procedures carried out in the study’s patients group.

Keywords: anesthesics, local; collagen; scars

Introduction: Molluscum contagiosum is a dermatovirosis caused by a poxvirus. In the literature there are descriptions of different therapeutic approaches of this infection.
Objective: To evaluate the efficacy of imiquimod – isolated and associated with curettage – in the treatment of molluscum contagiosum.
Methods: Group A: 20 patients used 5% imiquimod cream 3 times a week for 6 weeks. Group B: 10 patients used a creamy base 3 times a week, for 6 weeks. After the initial 6 weeks, all patients underwent curettage.
Results: Group A: 31% decrease in the number of lesions in the 6th week, with a curettage effectiveness of 97.6%; Group B: 4.8% increase in the number of lesions in the 6th week, with a curettage effectiveness of 81.1%. The mean value for the pain level during curettage was 1.8 for Group A and 3.0 for Group B.
Conclusions: Due to the facts that the rate of cure of contagious molluscum lesions increased and the pain decreased when the curettage procedure was conducted after the use of the immunomodulator, it was possible to conclude that the association of 5% imiquimod cream to the curettage may be a therapeutic possibility.

Keywords: Molluscum Contagiosum; Dermatology; Dermatologic Surgical Procedures

Introduction: Skin cancer is the most common type of cancer in the world. It is classified into melanoma (corresponding to 4% of cases) and non-melanoma types: basal cell carcinomas (70 to 80% of cases) and squamous cell carcinoma (25% of cases). The Brazilian Society of Dermatology conducts the National Campaign Against Skin Cancer on a yearly basis, aiming at diagnosing and providing early treatment to the neoplasia.
Objective: To demonstrate the incidence of lesions suspicious of skin cancer in selected patients originated from the 2016 National Campaign Against Skin Cancer, at the dermatologic clinic of a university hospital located in the Brazilian State of São Paulo’s midlands.
Methods: Two hundred and thirty patients were examined, of which 24 were selected with 22 undergoing biopsy of the suspected lesions.
Results: Sixteen basal cell carcinoma cases, one squamous cell carcinoma and one melanoma were confirmed through anatomopathology.
Conclusions: Notwithstanding the small sample, it was possible to conclude that the results found are compatible with those of the literature reviewed. It is of paramount importance to carry out the campaign as a way to streamline the population’s access to a dermatologist, which results in the early diagnosis and treatment of skin cancers.

Keywords: Melanoma; carcinoma, basal cell; skin neoplasms; neoplasms, squamous cell; health promotion

Introduction: The use of light emitting diodes (LEDs) is a new modality of treatment for acne. The blue and amber lights are indicated for the treatment of acne due to their bactericidal and cellular metabolism stimulation actions, respectively.
Objectives: To compare the effects of the combined blue and amber LEDs to those of the isolated blue LED in the treatment of acne.
Methods: A randomized, blind clinical trial was carried out with men and women distributed into 2 groups: Group 1 (blue LED) and Group 2 (blue + amber LEDs). The patients were treated in 6 sessions and qualitatively evaluated using 2 subjective tools: a questionnaire and the Visual Scale of Facial Perception and quantit==atively by counting the number of acne lesions.
Results: Ten volunteers took part in the study, obtaining a reduction of 1.7 in the psychosocial impact score and of 2.1 in the Visual Scale of Facial Perception, as well as an improvement in the lesions count, with 60% presenting slight improvement and 10% presenting moderate improvement.
Conclusions: It was possible to observe that the use of LED was effective in the two groups (both in the self-assessment of improvement and in the reduction of the number of lesions), meaning it can be considered an effective and safe therapy for the management of acne.

Keywords: skin; acne vulgaris; lasers; light; phototherapy; physical therapy specialty; psychosocial Impact

Cryolipolysis is known worldwide as an effective and safe treatment for the reduction of localized body fat. A review of the current literature on the subject was carried out, including possible complications of the technique.

Keywords: cryotherapy; adipose tissue; therapeutics

The dermatologist's clinical practice is based on the analysis of cutaneous lesions that is carried out mainly by clinical observation, and currently supplemented with tests such as dermoscopy and confocal microscopy. Despite its low cost, the Wood's lamp has been decreasingly used as an auxiliary diagnostic method. The authors of the present study describe several cases of use of the Wood's lamp where it provided valuable assistance to the dermatologist, aiming at encouraging the use of this device in the daily practice.

Keywords: fluorescence; diagnosis; malassezia; propionibacterium acnes; porphyrias; vitiligo; melanosis; erythrasma; corynebacterium; tinea capitis

Sarcoidosis is a non-infectious granulomatous disease of unknown etiology in which environmental, infectious, immunological, and genetic factors appear to be correlated. Clinical manifestations can occur in any organ, however there is predominance in the lungs and in intrathoracic lymph nodes. The cutaneous involvement of the disease occurs in roughly 25% of cases, with cutaneous filling procedures figuring as a potential trigger. The authors of the present article report a case of a patient who had granulomatous lesions on the face following cutaneous filling with hyaluronic acid. In the investigation of cutaneous lesions, the patient presented diagnostic criteria for sarcoidosis, with extensive pulmonary involvement.

Keywords: sarcoidosis; granuloma; hyaluronic acid

Oncologic ear resection can create partial skin and / or cartilage defects that make reconstruction of this site difficult and challenging. Several techniques have been described, however few cases of surgery for defects in the cauda helicis have been reported. The authors describe an interpolation flap in this anatomical location for the correction of a defect secondary to the excision of a basal cell carcinoma.

Keywords: surgical flaps; ear; carcinoma, basal cell

Kaposi's sarcoma is a rare multicentric neoplasm originating from endothelial cells, with cutaneous and extracutaneous manifestation. The present paper describes a case of an uncommon clinic variant of a Kaposi’s sarcoma in a 32 year-old male patient bearer of acquired immunodeficiency syndrome (AIDS), with regression after undergoing combined treatment with antiretroviral therapy and radiotherapy.

Keywords: sarcoma, kaposi; herpesvirus 8, human; acquired immunodeficiency syndrome; keloid

Among the diverse reconstruction alternatives used in surgical wounds, those employing cutaneous grafts are implemented when the closure – primary or by second intention – is unfeasible or, due to other factors, flaps are not recommend. The repair of surgical wounds using partial thickness graft obtained from the scalp with a flexible blade is described in 3 cases of conventional exeresis (2 basal cell carcinomas in the nasal region and 1 case of squamous cell carcinoma on the dorsum of the hand). The technique yielded good aesthetic outcomes, both in the receiver and donor areas.

Keywords: dermatologic surgical procedures; skin neoplasms; scalp; carcinoma, basal cell; carcinoma, squamous cell; skin grafts

Angioma serpiginosum is a rare and benign vascular ectasia that clinically arises as small red or purple dots, with serpiginous configuration. Controlled light pulses or intense pulsed light is the light source that emits high energy light within the continuous waves spectrum from 500nm to 1,200nm. Among its characteristics is the indication for the treatment of vascular lesions, which is the oxyhemoglobin chromophore’s pigment. This paper describes a case of a 12-year-old patient with angioma serpiginosum on the right arm that receded after 6 intense pulsed light sessions.

Keywords: intense pulsed light therapy; hemangioma; capillary hemangioma; vascular diseases