Unattractive periauricular widened or hypertrophic scars can result from the tension on rhytidoplasty incision sutures. During a 5-year retrospective study, 10 female patients with such scars were treated with the periauricular ring technique. Polytetrafluoroethylene and double 2-0 mono nylon threads were used in 6 and 4 cases, respectively, introduced with a fascia lata non-bevelled needle . Following the scar exeresis, the borders were approximated and the ring tied and attached to the temporal muscle fascia.The outcomes were satisfactory. In 2 cases the threads were removed without altering the scars’ final aesthetic result.

Keywords: CICATRIX, CICATRIX HIPERTROPHIC, RHYTIDOPLASTY, EAR

Introduction: The dermis is mainly composed of the extracellular matrix and fibroblasts that produce collagen types I and III, and elastic fibers. Objective: To verify through a prospective, comparative controlled clinical study whether there is an increase in the production of collagen fibers in healthy human skin after the injection of autologous fibroblasts in the dermis. Methods: Two skin fragments were collected from the right retro-auricular region of four women aged between 25 and 60 years. In one of the fragments, histology was carried out with Hematoxylin-Eosin and Picrosirius to qualify and quantify the collagen fibers (Control Group). A second fragment underwent enzymatic digestion in the laboratory aimed at extracting and culturing fibroblasts. After satisfactory growth (1 x 107 cells / ml) the cultured fibroblasts were injected in the left retro-auricular region of the patients (Study Group). Three months after biopsies were harvested from this region, they were subsequently stained with Hematoxylin-Eosin and Picrosirius for comparative study between the two groups. Results: Statistical analysis of the number of collagen fibers in the three layers of the dermis - upper, middle and deep - comparing the study and control groups, showed that the mean and median observed after the injection of the cells were greater than those observed before the injection. Conclusion: The injection of fibroblasts results in an increase in the amount of collagen fibers in all regions of the dermis, with the increase being greater in the deeper regions.

Keywords: FIBROBLASTS; CELL-AND TISSUE-BASED THERAPY; COLLAGEN

A woman with type I diabetes and Hashimoto’s disease presented necrobiosis lipoidica at 15 years of age. Cyclosporine 100 mg/day was prescribed; however, an abscess in the inguinal region led to treatment interruption. Then, she tried dimethyl fumarate at increasing doses up to 120 mg/day. The lack of results led to the discontinuation of the therapy. The third attempt was isotretinoin 40 mg/day for eight months, with wound healing. Recently, after a knee scar repair surgery, necrobiosis lipoidica lesions appeared at the suture site. The patient received isotretinoin 40 mg/day again, and the lesion regressed in three months.

Keywords: Necrobiosis Lipoidica; Diabetes Mellitus, Type 1; Bacterial Infections

We developed a narrative literature review on the association of fat grafting and hair transplantation using the Follicular Unit Extraction (FUE) technique in scalp scars. Data were collected from studies found in Medline, Lilacs, and IBECS databases. Bibliographical records of several authors who researched mesenchymal cells in adipose tissue were cited, describing the techniques used. The conclusion was that the two-stage hair transplantation technique, with previous fat transplantation, is effective, according to the reviewed articles.

Keywords: Stem Cells; Mesenchymal Stromal Cells; Adipose Tissue; Hair transplantation