A present a clinical case of a rare variant of dermatofibroma (aneurysmatic type), is presented in a 72-year-old female patient, the lesion was located in the right arm’s flexural fold, resulting from mesenchymal proliferation associated with blood vessels and tissular hemorrhage, with its own well defined histological characteristics. The objectives are to describe the rarity of the lesion and its histopathologic importance, when compared to other benign and malignant tumors in the differential diagnosis, in addition to the terminology currently used.

Keywords: BENIGN FIBROUS HISTIOCYTOMA, MALIGNANT FIBROUS HISTIOCYTOMA, HEMOSIDERIN

A clinical case of subungual squamous cell carcinoma, in which a tumor had been located in the medial fold of the left thumb for 4 years, is described in a 89-year-old male patient.The objectives of this study are to draw attention to the rarity of the subungual location of the tumor – highlighting the differences in diagnosis compared with benign lesions – and the importance of pain as a symptom, which may help diagnose the condition early and facilitate a better prognosis and lower morbidity. Additionally, we discuss the more frequently used therapeutic approaches, based on a review of the literature on radiation therapy, Mohs Micrographic Surgery and amputation.

Summary: Acquired digital fibrokeratoma is a rare benign fibroepithelial condition, which typically occurs as a solitary asymptomatic nodule in fingers and toes. The authors report the clinical case of a female patient affected by two digital fibrokeratomas in the 4th and 2nd left fingers, respectively.

Keywords: NEOPLASMS, FIBROEPITHELIAL; FIBROMA; FINGER INJURIES.

Koenen tumors are nail fibromas included among the main diagnostic criteria of tuberous sclerosis. Elongated and thin papules, firm, with smooth surface and broad base characterize these lesions, which are slightly erythematous and present varying sizes. Koenen tumors commonly affect toenails and result in aesthetic and functional concerns associated with deformities, pain, and bleeding. Several therapeutic options are described for Koenen tumors; however, there is a lack of consensus in the literature regarding standard treatment. We report the case of a patient who underwent surgery with excellent outcomes. Additionally, we discuss the advantages and disadvantages of each therapeutic modality.

Keywords: Dermatologic Surgical Procedures; Fibroma; Nails; Tuberous Sclerosis

INTRODUCTION: Cutaneous cancer has a high incidence, can be screened with dermatological clinical examination and confirmed by cutaneous biopsy.
OBJECTIVE: To verify the prevalence of pathological diagnoses for suspected non-melanoma skin cancer (NMSC) lesions in a Reference Service.
METHODS: Observational and cross-sectional study. Patients with indication of skin biopsy for suspected NMSC were included. Variables analyzed: age, gender, personal history of skin cancer, number of biopsies, biopsy site, and pathological outcome, divided into Group 1 (neoplastic lesions); Group 2 (premalignant lesions), and Group 3 (benign lesions).
RESULTS: A total of 287 patients, with an average of 1.33 biopsies per patient. The median age in the sample was 71 years, and 56.1% were women. Personal history of skin cancer: 44.95%. General sample: group 1: 62%; group 2: 21% and group 3: 17%. Neoplasms found: 68% were BCC, 30% were SCC, and other neoplasms: 2%. In the group of premalignant lesions: mainly actinic keratosis; in the group of benign lesions: diagnostic variety. The cephalic segment was the most frequently biopsied topography (58%).
CONCLUSIONS: In this study, we showed a higher incidence of skin cancer in women, with the majority of elderly patients being the most frequent diagnosis of BCC.

Keywords: Basal Cell; Biopsy; Carcinoma; Neoplasms; Skin neoplasms; Squamous cell.