Injectable fillers have long been used for cosmetic purposes and in HIV induced lipodystrophy patients. A foreign body granuloma may be a side effect of the application of absorbable products/temporary and most often the nonabsorbable/permanent fillers. It is not possible to predict the formation of these granulomas, and it may occur regardless of the application technique. In this article we describe the surgical treatment of a patient with multiple granulomas caused by intradermal injection of PMMA in the face, with poor response to conservative treatments, and severe psychosocial impairment due to this unsightly and disfiguring complication.

Keywords: POLYMETHYL METHACRYLATE; GRANULOMA; AMBULATORY SURGICAL PROCEDURES

Angiokeratomas are vascular malformations constituted by telangiectasia of preexisting vessels. They are not classified as angiomas. It is the rarest variant of angiokeratomas, with few cases in the literature. The mechanism of development of these lesions has not yet been fully elucidated. Small lesions can be treated with electrosurgery, curettage, or cryosurgery. Larger lesions require deep surgical excision, and depending on the size and depht of the lesion, direct closure, flap, or grafting. CO2 or argon laser are considered other treatment options. In this case report we describe a classic case of circumscribed angiokeratoma, with onset at birth, and progressive growth.

Keywords: Ambulatory surgical procedures; Dermatology; Vascular malformations

In the aging process, the intracellular routes that regulate collagen homeostasis are influenced by the exposome, resulting in its degradation and decreased synthesis, leading to sagging skin. Current evidence indicates that oral collagen supplementation may promote wrinkles reduction in the eye area, wound healing, skin elasticity and hydration improvement, enhancement of cellulite, some dermatitis, and nails fragility. Large-scale and methodologically more robust studies are still needed to consider the use of oral collagen as an effective adjuvant treatment to different dermatological conditions.

Keywords: Collagen; Skin; Dietary supplements