This is case report of lichen planus pigmentosus associated with classical lichen planus treated with intense pulsed light. Intense pulsed light technology has been used successfully for removal of various benign pigmented skin lesions and, in this rare case, it has proved its effectiveness.

Keywords: LICHEN PLANUS, PHYSICOCHEMICAL TREATMENT, PHYSICAL-CHEMICAL TREATMENT, HYPERPIGMENTATION

Introduction: The interest in minimally invasive procedures for facial rejuvenation fos- tered the development of the cutaneous filling technique to treat wrinkles and folds. Hyaluronic acid is one of the most popular fillers,as it is considered the least immuno- genic and safest in its category.
Objective: To evaluate and compare the efficacy,safety and duration of effect after the application of the filler CRMDex® in nasolabial folds,in one session versus two sessions.
Methods: Open clinical trial,with the randomization of nasolabial folds and comparison between two techniques.Women,aged 30 to 60 years old (n=30),presenting with accen- tuated symmetric nasolabial folds of minor to moderate degrees were subjected to intra- dermal injections of the same volume of CRMDex®.Three independent dermatologists evaluated the effectiveness of the treatment using the Wrinkle Severity Rating Scale.
Results: There was no difference in treatment effect for one versus two sessions.Both groups achieved a reduction of at least one degree according to the severity scale,and had a similar duration of the filling effect.The more frequent local adverse events (pain,ery- thema and edema) occurred during the injection and improved spontaneously.
Conclusions: There was no improvement in therapeutic response with the injection of smaller volumes per session.It seems that higher filler volumes may increase the risk of local adverse events.

Keywords: HYALURONIC ACID, BIOLOGICAL REACTIONS, DERMIS, CICATRIX

Keloids are an excessive proliferation of dermal fibroblasts following a skin injury, which are difficult to treat. Isolated measures present a low rate of efficacy, while combined techniques lead to better results.A case of keloidal scar in the pubic region after a myomectomy surgical incision is described. The scar was divided into three parts, each of which was treated with intralesional injections of 5- fluorouracil, corticosteroid and 5-fluorouracil combined with corticosteroid.

Keywords: SCAR, KELOID, THERAPY

The use of injectable hyaluronic acid (HA) in wrinkle filling and facial volumization is well established in the dermatological practice. While complications are rare, techniques for their management should be known by the dermatologist. Nodules may occur with the use of deeper application fillers, and the treatment is similar to that used for the more superficial and less viscous fillers. The use of a thinner cannula may reduce this risk, especially in areas where the dermis is thinner.

Keywords: HYALURONIC ACID; ACCIDENTS; DERMIS.

Filler injections are among the most popular cosmetic procedures performed worldwide. Although fillers have a safety profile, there has been a rise in litigation as a result of treatments in the USA. In the Brazilian scenario, the number of non-surgical procedures has increased in the past years, mainly due to the increase of filler options available in the Brazilian market, as well as in the type of professionals allowed to perform injectable procedures. Therefore we sought to review the related literature regarding semi-permanent and temporary fillers adverse effects and outline a practical guide for complications avoidance, diagnosis and management.

Keywords: GRANULOMA; ISCHEMIA; ESTHETICS; HYALURONIC ACID; DERMIS; SUBCUTANEOUS FAT; BIOFILMS; INFECTION

The concept of facial rejuvenation currently includes a three-dimensional perspective, which recognizes as signs of aging not only the loss of the skin's texture and the emergence of expression wrinkles, but also the volumetric losses secondary to bone remodeling and redistribution of facial fat. This article was aimed at reviewing the literature on poly-L-lactic acid for facial rejuvenation – including its indications, injection techniques, expected results and possible adverse effects – and offer practical guidelines, based on the authors' 12-year experience with the product.

Keywords: SKIN AGING; INJECTIONS; COLLAGEN