Juvenile xanthogranuloma is a form of non Langerhans cell histiocytosis that mainly affects children. It usually emerges as asymptomatic yellow-brownish papules. The diagnosis is clinical and confirmed by histology. Due to its trend to involute, treatment is usually not recommended. Dermoscopy arises as a noninvasive diagnostic tool that reveals a typical pattern for this condition.

Keywords: XANTHOGRANULOMA, JUVENILE; DERMOSCOPY; HISTIOCYTOSIS, NON-LANGERHANS-CELL

Amyloidosis is characterized by the deposition of a modified protein. It can affect the skin by accumulating in the papillary dermis. In general, it develops with brownish maculae predominant in the interscapular region, and rarely coursing with generalized forms. This report describes a 59 year-old female patient who had had a spot in the lower back for 43 years, which in the last 8 years had progressively spread for the entire body. Dermoscopy has proven extremely effective in locating the various foci of pigmentary incontinence, which together with apoptotic keratinocytes constitute the pathophysiological basis for the formation of the amyloid protein.

Keywords: AMYLOIDOSIS; CONGO RED; DERMOSCOPY

Kaposi's sarcoma is a rare multicentric neoplasm originating from endothelial cells, with cutaneous and extracutaneous manifestation. The present paper describes a case of an uncommon clinic variant of a Kaposi’s sarcoma in a 32 year-old male patient bearer of acquired immunodeficiency syndrome (AIDS), with regression after undergoing combined treatment with antiretroviral therapy and radiotherapy.

Keywords: sarcoma, kaposi; herpesvirus 8, human; acquired immunodeficiency syndrome; keloid

Systemic sclerosis (SE) is an autoimmune disease of the connective tissue. Of unknown etiology, it is characterized by sclerosis (fibrosis), which affects the skin, blood vessels and internal organs. The diagnosis is confirmed by a compatible clinical picture, autoantibody research and capillaroscopy of the nail bed. The present report highlights the importance of the dermatologist physician in the diagnosis of systemic diseases. Based on the observation of the skin – which is visible and palpable in all of its dimensions – and in the interpretation of all its signs, it is possible to conclude that it can reveal early internal disorders that could develop unnoticeably.

Keywords: Scleroderma, systemic; Fibrosis; Autoantibodies