Neurofibromatosis type 1, also known as von Recklinghausen neurofibromatosis, is an autosomal dominant disorder that affects 1 in 3,000 newborns. Approximately 50% of neurofibromatosis type 1 patients have no family history of the disease. The tongue, the alveolar ridge of the buccal mucosa, gums, lips, palate, floor of the mouth, and pharyngomaxillary fossa can be affected by tumors associated with this condition; the tongue is the most common site. We report the case of a 29-year-old female patient with neurofibroma in the tongue, highlighting the possibility of disease manifestations in the oral cavity and differential diagnoses.

Keywords: NEUROFIBROMATOSIS 1; NEUROFIBROMA, PLEXIFORM; NEUROFIBROMA; TONGUE NEOPLASMS.

Summary: Multiple cutaneous miliary osteoma is a rare condition characterized by ectopic bone tissue in the dermis and/or hypodermis. It usually occurs on the face, in individuals of 17 to 79 years old. Its etiology is still unknown. The present article reports the case of a female patient affected by a hardened, poorly delimited, papular plaque of dark brown hue and irregular surface, affecting the malar and mentonian regions. The patient sought medical care two years before the publication of this study, describing untreated acne since the age of 16. The papular plaque was composed of hyperchromic papular nodular lesions – some with white-yellowish hue. The diagnosis was confirmed histopathologically. Satisfactory therapeutic results were achieved with the use of 0.1% tretinoin cream.

Keywords: OSTEOMA; DECALCIFICATION, PATHOLOGIC; OSSIFICATION, HETEROTOPIC.

Proliferating Trichilemmal Tumor (PTT) is an uncommon benign neoplasm that usually affects adult women over 60 years old, preferably as a solitary nodule in the scalp. We report a case of PTT in a young woman presenting exuberant, asymptomatic scalp tumors 7 years ago, which recurred after surgical exeresis. The histopathology confirmed the diagnosis, and surgical excisions and clinical follow-up were performed. PTT appears to originate from the wall of trichilemmal cysts, from the isthmus of the hair follicle’s outer root sheath. Usually, it has benign biological potential with a low risk of malignancy and high recurrence. The therapy of choice is surgery.

Keywords: Cysts; Neoplasms; Scalp