Talon noir was first described in 1961 by Peachey as atraumatic petechial eruption characteristic of basketball players' heels, and were originally called calcaneal petechiae. It is a dermatosis linked to trauma, with asymptomatic lesions, marked by the presence of blood within the stratum corneum. It presents varied clinical manifestations, with the location depending on the involved provocative fac-tor. The present study describes a case of talon noir in a patient with psoriasis vulgaris and demonstrates the importance of the correlation of clinical, dermoscopic, and histopathological characteristics.

Keywords: BLOOD STAINS, NEVI AND MELANOMAS, FOOT

Adverse reactions associated with drugs presenting cutaneous manifestations are among the most common, expressing itself with multiple clinical aspects and causing significant morbidity. The fixed drug eruption (FDE) is a common adverse reaction with cutaneous involvement and is associated with the use of numerous drugs. Dipyrone is a drug with analgesic and antipyretic effects prescribed widely used in Brazil, however, it is known for its potential to triggering adverse reactions, including the FDE. This report shows an EMF case related to the use of dipyrone, with unique clinical presentation and correlate the clinical, histopathological and dermatoscopic found.

Keywords: DERMOSCOPY; FACE; PATHOLOGY

INTRODUCTION: Vitiligo is a dermatological condition that causes loss of skin pigmentation, significantly affecting patients' quality of life due to social stigma. Despite various therapeutic approaches, including topical treatments, systemic therapies, and phototherapy, many cases remain refractory.
OBJECTIVE: To report a series of cases to evaluate the effectiveness of autologous melanocyte grafting using the micropunch technique.
METHODS AND RESULTS: We selected 9 patients with stable and refractory vitiligo, totaling 15 surgeries. Of these, 93.3% showed some degree of repigmentation in the treated area, with the formation of a pigmentation halo around the grafts, as observed in post-surgical photographic follow-up. The inner arm was the most frequently used donor area (60%). The complications were minimal: 1 patient (6.7%) developed hypertrophic scarring in the donor area; 3 patients (20%) developed the "cobblestone appearance" in the recipient area, with 1 case resolving spontaneously after 6 months. There was also partial graft loss in 1 patient (6.7% of surgeries).
CONCLUSION: The results indicate that the micropunch technique is a viable and safe alternative for managing stable vitiligo, offering a new therapeutic option for cases refractory to conventional treatments.

Keywords: Vitiligo; Transplantation, Autologous; Skin Pigmentation.