The authors present the surgical reconstruction after excision of two synchronous adjacent basal cell carcinomas in the left infraclavicular region, using the Zetaplasty transposition flap technique. Being versatile and simple to perform, Zetaplasty was proven a useful solution for the reconstruction of double defects within a single procedure.

Keywords: CARCINOMA, BASAL CELL; SKIN NEOPLASMS; SURGICAL FLAPS

INTRODUCTION: Nutricosmetics have been used as supplements for hair growth in the treatment of non-cicatricial alopecia. However, there are no studies on using of these products in individuals under 18 years of age.
OBJECTIVE: To assess the efficacy and tolerability of using a nutricosmetic product based on proteoglycans in individuals under 18 years of age with non-cicatricial alopecia.
METHODS: This is a clinical, uncontrolled, and prospective trial. Patients with non-cicatricial alopecia, of both sexes, aged between 6 years and 18 years, received nutricosmetics containing proteoglycan for six months. Three dermatologists independently evaluated standardized pre and post-treatment photos. A hair count was performed in a scalp area of 1 cm², and the patients answered a questionnaire about improvement or worsening.
RESULTS: Eleven patients (100% women) were included. Ten (91%) showed improvement after six months, observed through photographic evaluation, hair count, and self-assessment. No patient presented allergies. Two patients had transient epigastric pain.
CONCLUSIONS: The use of proteoglycans-based nutricosmetics was effective and well-tolerated in children and adolescents with non-cicatricial alopecia.

Keywords: Alopecia; Hair follicle; Proteoglycans; Treatment outcome

Chromoblastomycosis is a chronic granulomatous infection caused by dematiaceous fungi with varied clinical presentations, which may represent a therapeutic challenge. In this report, we present a case of chromoblastomycosis in a localized form, with a long evolution, in an elderly patient, resistant to previous drug therapies, successfully treated by the association of a physical method with systemic pharmacological treatment, which allowed the use of a reduced dose of the drug.

Keywords: Chromoblastomycosis; Cryosurgery; Itraconazole