NK/T cell lymphoma is a rare, aggressive, non-Hodgkin tumor that is closely related to the Epstein-Barr virus. It has a poor prognosis and poor response to treatments. We report the case of a 91-year-old woman with a history of injury in the nasal region for three months. Histological study showed diffuse infiltration of the dermis by small and atypical lymphoid cells and positive immunohistochemistry for Ki-67, CD30, and CD3 (cytoplasmic). Due to the fast growth of the lesion and the high morbidity of the neoplasm, the patient was referred to the hospital for assistance but died before starting treatment.

Keywords: Epstein-Barr Virus Infections; Lymphocytes; Medical oncology; Extranodal T-NK Cell Lymphoma; Lethal Midline Granuloma

Cylindroma is a rare benign neoplasm of probable origin in the eccrine sweat glands and is characterized by papular and nodular, painless, slow-growing lesions, generally located on the head, neck and scalp. When multiple, they can be part of hereditary syndromes. The authors report the case of a patient with a solitary nodulation on the scalp, presenting pathological examination compatible with cylindroma. The lesion was excised, with satisfactory results and no recurrence.

Keywords: Sweat Gland Neoplasms; Skin Neoplasms; Deubiquitinating Enzyme CYLD.

Although primary cutaneous amyloidosis (PCA) is prevalent worldwide, it is underdiagnosed. Among the subtypes, nodular amyloidosis (NA) is the rarest. There is no consensus in the literature; treatment is challenging, and no therapy has been proven effective. The authors report the case of a patient with a nodule in the nose, whose anatomopathological examination was compatible with amyloidosis, with no evidence of systemic disease. It was then classified as nodular PCA. The lesion was excised satisfactorily. It was concluded that surgical removal is an effective therapy for the treatment of NA.

Keywords: Amyloidosis; Amyloid; Congo Red