Surg Cosmet Dermatol. 2018;10(3):230-237
INTRODUCTION: Cutaneous flaps can be complicated by both ischemia and estrogen deficiency. In this manner, it is desirable to improve the healing process with the use of medicinal plants, such as Aloe vera.
OBJECTIVE: To evaluate the effect of Aloe vera’s glycolic extract on skin flaps performed on oophorectomized rats.
METHODS: Cutaneous flap was performed in 20 animals, distributed in four groups, submitted to differentiated procedures, with microscopic (21st day) and macroscopic analysis (seventh and 14th day).
RESULTS: Microscopic variables were not significant. Two groups showed improvement in the general condition of the wound, and only one presented significant closure of the wound.
CONCLUSIONS: The Aloe vera extract yielded promising parameters regarding the macroscopic aspects; however further studies are necessary for a better evaluation.
Keywords: Aloe; Wound healing; Estrogens
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