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Cutaneous metastasis of follicular thyroid carcinoma mimicking pyogenic granuloma

Caroline Paias Ribeiro1; Fabiana Oliveira da Silva1; Ticiana de A. Castelo Branco Diniz1; Mario Cezar Pires1,2; Neusa Yuriko Sakai Valente1,3

DOI: https://doi.org/10.5935/scd1984-8773.20181031985

Abstract

Follicular thyroid carcinoma is a well-differentiated tumor, and is considered the second most common subtype of thyroid cancer. Its metastasis usually arises hematogenously — mainly to the lungs and bones — and is considered rare when it occurs cutaneously. The authors report a case of a patient with follicular thyroid carcinoma for 5 years who noticed an erythematous, friable exophytic nodular lesion measuring 1cm on the scalp with 7 months of development, simulating a pyogenic granuloma. Biopsy analysis revealed an adenocarcinoma with glandular differentiation and colloid material in the lumen. The immunohistochemical profile was positive for CK-7 and thyroglobulin, favoring the diagnosis of cutaneous metastasis of primary thyroid neoplasia.


Keywords: Dermatology; Granuloma, Pyogenic; Neoplasms; Neoplasm metastasis



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