Surg Cosmet Dermatol. 2016;8(4):73-75
Nodular hidradenoma is a benign adnexal neoplasia. Recently a subdivision in two groups has been suggested: tumors with eccrine differentiation or poroid hidradenoma and tumors with apocrine differentiation or clear cell hidradenoma. They present as well delimited dermal nodule, with a variable dimension between 0.5 and 3 cm, asymptomatic, slow growing and endophytic. Histopathology shows typical biphasic cell pattern, with polyhedral cells with eosinophilic cytoplasm and large cells with abundant clear cytoplasm and small nucleus. Malignant transformation is rare. We report a case of clear cell hidradenoma with unusual clinical characteristics and a review of the literature.
Keywords: NEOPLASMS, ADNEXAL AND SKIN APPENDAGE; SKIN NEOPLASMS; ACROSPIROMA; SURGICAL FLAPS