Introduction: Being healthy corresponds to a state of absolute well-being. Scars are examples of con- ditions that endanger patients’ emotional integrity, compromising their quality of life. Consequently, there are several therapeutic alternatives aimed at alleviating aesthetic disorders. Microneedling stimu- lates collagen production, improving the healing effect in the induced cutaneous injury.
Objective: to evaluate the effect of microneedling in the scars of surgically induced cutaneous wounds in rats.
Methods: Twenty-four male rats were distributed in five study groups. A surgically induced incision was inflicted on the animals’ dorsa in all study groups, with the healing processes being followed up until completion.The study groups GC-14 and GC-30 served as controls for the groups GCM-14 and GCM-30, respectively
Results: Reepithelialization and absence of granulation tissue were identified in 100% of the groups. Regarding the proportion of fibrosis, mean reductions of 19% and 4% were observed in GCM-14 and GCM-30, respectively. There was a stimulus to the production of type I and III collagen in the groups that underwent microneedling, with a greater amount of type I collagen in GCM-14 (62.1%) as compared to its control (37.8%).
Conclusions: Microneedling was effective in stimulating increased production of collagen fibers in 14 days, suggesting this treatment tends improve scars.

Keywords: Cicatrix; Collagen; Models, animal

INTRODUCTION: Cutaneous flaps can be complicated by both ischemia and estrogen deficiency. In this manner, it is desirable to improve the healing process with the use of medicinal plants, such as Aloe vera.
OBJECTIVE: To evaluate the effect of Aloe vera’s glycolic extract on skin flaps performed on oophorectomized rats.
METHODS: Cutaneous flap was performed in 20 animals, distributed in four groups, submitted to differentiated procedures, with microscopic (21st day) and macroscopic analysis (seventh and 14th day).
RESULTS: Microscopic variables were not significant. Two groups showed improvement in the general condition of the wound, and only one presented significant closure of the wound.
CONCLUSIONS: The Aloe vera extract yielded promising parameters regarding the macroscopic aspects; however further studies are necessary for a better evaluation.

Keywords: Aloe; Wound healing; Estrogens