Introduction: The botulinum toxin is a valuable option for the treatment of dynamic facial wrinkles. The Lanzhou botulinum toxin type A (LBTX-A) was introduced in China in the early 90’s and approved in Brazil in 2003. Objective: Evaluate the efficacy and tolerability of LBTX-A for the cosmetic treatment of dynamic wrinkles of the upper face. Material and Methods: In a prospective, open-label, multicenter study, 110 subjects of both sexes (aged from 25 to 65 years) were treated with a total of 53 U of LBTX-A each, distributed in fi fteen sites in the frontal, corrugator, procerus, orbicular ocular lateral muscles. The patients were reviewed 7 times within 180 days. Efficacy was assessed by electromyography, photographic analysis and the investigator’s and patient’s opinions. Tolerability was assessed by the incidence of adverse events.Results: Two weeks post-injection, 94% of the treated patients considered the result as good or excellent. Results lasted 90 days in most cases. After injection, most patients reported mild or no pain, and minimal and reversible side effects as facial edema (6 patients), stuffiness feeling (3 patients) and eyelid ptosis (2 patients). Conclusions: We conclude that LBTX-A is effi cient and well tolerated for the treatment of dynamic facial lines.

Keywords: BOTULINUM TOXIN TYPE A, INJECTABLES, WRINKLES, FACIAL DYNAMIC LINES

The lower limbs defects reconstructions are complex and impose a challenge for the reconstructive surgeon. The use of local fasciocutaneous flaps can be helpful when dealing with these defects. We report the case of two patients who underwent calcaneal reconstruction surgery using a medial plantar artery flap after the resection of acral melanoma. This flap provides a resistant and long-lasting tissue with a neurovascular sparing technique. The preserved sensitivity contributes to good long-term outcomes. The neurovascular flaps, such as medial plantar artery flap, promote good adaptation and healing regarding foot and heel defects.

Keywords: Plastic surgery; Lower extremity; Melanoma; Surgical flaps