Introduction: Primary cutaneous sarcomas are rare mesenchymal cancers with histopathological heterogeneity. Angiosarcomas are an uncommon cutaneous malignant sarcoma sub-type that effect mainly elderly male patients.Their location is primarily cephalic, and they present as multifocal lesions which lead to local edema, bleeding and ulceration. Aggressiveness, fast growth and undefined surgical margins explain the high rates of recurrence.We describe a case of primary angiosarcoma of the scalp in an elderly female patient, who was being treated with a multidrug therapy for lepromatous leprosy.The combination of angiosarcoma and leprosy is uncommon, and the absence of similar reports in the literature motivated the description of this case.

Keywords: SKIN NEOPLASMS, SARCOMA, LEPROSY, LEPROMATOUS

Extramammary Paget's disease is a rare cutaneous neoplasm typically occurring in the vulva of Caucasian women after menopause. Clinically, the most common symptom is pruritus, when an erythematous, desquamative and eczematous lesion can be observed. Due to the rarity and nonspecific appearance of the disease, it can be confused with other dermatological conditions, delaying diagnosis. The present case demonstrates a form of vulvar extramammary unilateral Paget's disease confirmed by anatomical pathologic and immunohistochemical study. The standard treatment used for the disease in this case was surgical and the patient underwent complete excision of the lesion, with continued monitoring every six months.

Keywords: GENITAL NEOPLASMS, FEMALE; VULGAR NEOPLASMS; VULVAR DISEASES; PAGET DISEASE, EXTRAMAMMARY.