Described by Jadassohn and also known as organoid nevus, nevus sebaceous is considered a hamartoma that exhibits follicular, sebaceous, eccrine and apocrine malformations of varying degrees. Between 10% and 30% of patients with sebaceous nevi of Jadassohn are at risk of developing cutaneous or adnexal neoplasia during adulthood. The authors describe the case of a patient with nevus sebaceous of Jadassohn associated with multiple tumors (benign and malignant) of different strains, highlighting the importance of the dermatologist physician’s knowing this entity and how to perform an examination of the scalp.

Keywords: Carcinoma, Basal Cell; Hamartoma; Neoplasms; Nevus sebaceous of Jadassohn

Cutaneous diffuse large B-cell lymphoma, leg type, is a rare, aggressive, and poorly prognostic neoplasm. It corresponds to 10-20% of cutaneous B-cell lymphomas and mainly affects the lower limbs of older women. We report the case of an 81-year-old woman with painful, fast-growing nodules and tumors in her left leg. Histopathological and immunohistochemical findings, associated with the absence of extra-cutaneous involvement during staging, concluded the diagnosis of cutaneous diffuse large B-cell lymphoma, leg type. The rarity of this limphoma, its typical clinic and epidemiology, and the excellent response to treatment motivated this report.

Keywords: Immunohistochemistry; Diffuse; Lymphoma non Hodgkin; Lymphoma large B-cell, Neoplasms; Therapeutics

Exogenous ochronosis is a stigmatizing dermatosis characterized by asymptomatic, bluish-black, or grayish macules in photoexposed areas. Associated with the prolonged use of hydroquinone for the treatment of dyschromias, it has a broad therapeutic arsenal, but the results are unsatisfactory and/or costly. We report the case of a female patient with histologically proven exogenous ochronosis who underwent dermabrasion associated with the use of tretinoin and topical corticosteroids with surprising results after three months of follow-up to demonstrate the possibility of therapeutic success with a low-cost technique and an outpatient clinic procedure.

Keywords: Ochronosis; Therapeutics; Dermabrasion