This study demonstrated the clinical and histologic result of the treatment of one disseminated superficial actinic porokeratosis patient with non-ablative fractional laser. The patient was treated with seven sessions of 1340-nm Nd:YAP laser, with 4 or 5 week-intervals. Biopsies and photographs were performed before and after treatment, which was well tolerated and lead to improvement in the erythema and texture of the lesions. There was a 1-year follow-up. Histopathologic examination after treatment revealed little changes in the cornoid lamella.

Keywords: Biopsy; Laser Therapy; Lasers; Porokeratosis

INTRODUCTION: Melasma is a recurrent and challenging dermatosis despite several clinical and interventional therapeutic approaches.
OBJECTIVE: This study aims to assess the safety and efficacy of using a bleaching cream in the period immediately after serial surface peels.
METHODS: Five women with melasma used a cream containing bleaches, moisturizers, and tranquilizers during the treatment period with serial surface peels. We assessed them in D0, D7, D30, D37, D60, D67, and D90 through photographs, record of the physician’s and patient’s opinion, description of adverse events, need to interrupt using the product, and the MELASQol questionnaire.
RESULTS: We observed improved hydration, skin quality, and bleaching, with little discomfort and a significant reduction in MELASQol scores, with statistical evidence.
CONCLUSIONS: The use of a topic cream with bleaching and tranquilizing properties is an effective and safe alternative to avoid interruption of melasma treatment during the period of serial surface peels.

Keywords: Chemexfoliation; Hyperpigmentation; Pigmentation disorders