Eficácia de um sérum despigmentante contendo ácido tranexâmico + niacinamida + 4-butilresorcinol e complexo de hidroxiácidos em comparação com hidroquinona no tratamento do melasma: ensaio clínico comparativo, randomizado e duplo-cego

Schalka, Sergio; Steiner, Denise; Furmanczyk, Marta; Brown, Anthony; Foyaca, Monica; Casals, Jaime Piquero

doi:10.5935/scd1984-8773.2026180564

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Efficacy of a depigmenting serum containing tranexamic acid + niacinamide + 4-butylresorcinol and hydroxy acids complex compared to hydroquinone in the treatment of melasma: a randomized, double-blind, comparative clinical trial

Sergio Schalka¹; Denise Steiner²; Marta Furmanczyk³; Anthony Brown³; Monica Foyaca³; Jaime Piquero Casals⁴

DOI: https://doi.org/10.5935/scd1984-8773.2026180564

Sergio Schalka¹; Denise Steiner²; Marta Furmanczyk³; Anthony Brown³; Monica Foyaca³; Jaime Piquero Casals⁴

1. Medcin Pesquisa Clínica, Osasco, São Paulo (SP), Brazil
2. Universidade de Mogi das Cruzes, Dermatology, Mogi das Cruzes, São Paulo (SP), Brazil
3. ISDIN, Innovation and Development, Barcelona, Catalonia, Spain
4. Dermacentric Health & Aesthetics, Barcelona, Catalonia, Spain

Corresponding author

Sergio Schalka
E-mail: sergio.schalka@medcin.com.br