High incidence of Xeroderma Pigmentosum in a countryside community in the state of Goiás, Brazil

We describe a settlement in the Araras District in central Brazil that presents a high incidence of Xeroderma Pigmentosum.Twenty patients have had clinical diagnoses compatible with this condition so far. Reports from surviving relatives suggest an additional 20 deaths linked to typical Xeroderma Pigmentosum symptoms.This is possibly the first report of its kind in the literature, due to the extension of the family factor prevalence, the patients’ age range and different characteristics of the clinical manifestations.

Keywords: XERODERMA PIGMENTOSUM, SKIN NEOPLASMS, GENETICS, EPIDEMIOLOGY