Surg Cosmet Dermatol. 2012;4(2):122-126
Introduction: The treatment of superficial burns is largely symptomatic, aimed at reducing the discomfort arising from the signs and symptoms and promoting skin repair. Some studies have evaluated the osmotic action mechanisms in the inflammatory process. Formulations with osmotic action can decrease the inflammatory exudate, which reduces the symptoms and even the risk of infections.
Objective: To evaluate the action of an osmotic action hydrogel for topical use in reducing the symptoms of a superficial, first-degree burn.
Method: Thirty-five patients with signs of first-degree burn were evaluated. The study product was applied on the injured area as a monotherapy. The analysis of symptoms (burning sensation), signs (erythema and edema), and clinical evaluation questionnaire were conducted after 5, 15, and 30 days, respectively. To evaluate the skin barrier''''''''s restorative effect, transepidermal water loss measurements were also carried out.
Results: Thirty-three patients completed the study. There were no adverse reactions. The reduction of symptoms and signs was significant (p < 0.001).The complete recovery of the skin barrier was observed at the end of the study.
Conclusion: The study product was effective and safe in reducing the signs and symptoms resulting from superficial burns.
Keywords: BURNS, OSMOSIS, SYMPTOMS, LOCAL