Surg Cosmet Dermatol. 2012;4(3):223-228
Introduction: The aging process of areas of the body that are frequently exposed to the sun has a clinical pattern different from that of facial photoaging. According to a number of published studies, the combination of retinaldehyde, glycolic acid, and nicotinamide presents promising results.
Objective: To evaluate the efficacy and safety of a new dermocosmetic formulation in the treatment of body photoaging.
Methods: Clinical, prospective, open, and monocentric study that evaluated 60 volunteers (phototypes I to III) with signs of photoaging in the neck region. Clinical and instrumental measurements (cutometry, corneometry, evaporimetry, and profilometry) were taken in the initial visits and 30 and 60 days after using the study product, which was applied at night, combined with the daytime application of sunscreen.
Results: After using the test product, the categories of clinical parameters (wrinkles, smoothness, hydration, and sagging) and biophysical hydration (measured using corneometry) presented statistically significant improvement (p < 0.05) in the intermediate and final visits. Despite showing improvement, the biophysical measurements of skin viscoelasticity and roughness were not statistically significant.
Conclusion: This combination was effective in the clinical improvement of body photoaging, and is an effective and safe alternative for treating this condition.
Keywords: SKIN AGING, COSMETICS, THERAPEUTICS
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