Surg Cosmet Dermatol. 2020;12(2):109-117
In the skin aging process, both intrinsic alterations, secondary to cell regeneration capacity loss resulting from chronological action, and extrinsic alterations, caused by to ultraviolet radiation exposure, can be observed. Treatments that restore collagen production and stimulate fibroblasts to synthesize and organize extracellular matrix are critical for morphogenesis, angiogenesis, and skin healing. Potential uses of products that stimulate collagen production, a component that plays a fundamental role in the extracellular matrix, represents a promising perspective for improving skin quality and its mechanical properties by introducing a new concept of therapeutic approach when treating changes caused by skin aging.
Keywords: Collagen; Hydroxyapatite; Skin Aging