Surg Cosmet Dermatol. 2026;18(2):1-4
Granular cell tumors are rare neurogenic neoplasms, usually benign, with a nonspecific clinical presentation. We report the case of a 70-year-old woman with an ulcerated nodular lesion on the arm, showing progressive growth, pain, and pruritus. Findings from complementary examinations, including magnetic resonance imaging, histopathological examination, and immunohistochemistry, confirmed, respectively, an expansive subcutaneous mass, a proliferation of polyhedral cells with granular cytoplasm, and positivity for the S100 protein, consistent with a diagnosis of granular cell tumor. The report discusses the importance of early diagnosis, complete surgical excision, and clinical follow-up to prevent recurrences and to monitor the rare risk of malignancy.
Keywords: Granular Cell Tumor; Schwann Cells; Neoplasms by Site
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