The application of platelet-rich plasma in the treatment of androgenic alopecia

Introduction: Introduction: Androgenic alopecia is the most common type of alopecia. It is characterized by alterations in the hair cycle, leading to progressive follicular miniaturization. Platelet-rich plasma, promotes angiogenesis in the tissue by action of growth factors, which stimulate the hair follicle Objective: To eveluate the hair growth in androgenic alopecia, through cell stimulation performed with the subcutaneous injection of platelet-rich plasma. Methods: Three injections of platelet-rich plasma were performed in 18 patients, at 21-day intervals.The evaluation was performed through comparative clinical photographs, dermoscopy, as well from responses to questionnaires. The Mann-Whitney test and Wilcoxon test were used to analyze the results. Results: For seven women who completed the study, the average improvement was 42.85% (patients) and 35.71% (external observer). For the 9 males, the average improvement was 25.55% (patients) and 18.88% (external observer). In Dermoscopy were observed thickening of hairs, improved local circulation and increased number of follicles. Conclusions: An effective and satisfactory response in androgenic alopecia was verified in relation to the platelet-rich plasma injection technique.

Keywords: ALOPECIA; PLATELET-RICH PLASMA; DERMATOLOGY