Polymethylmethacrylate (PMMA) filling in the lower limbs of a patient with lipodystrophy caused by antiretroviral drugs

The Highly Active Antiretroviral Therapy promoted a better quality of life for seropositive patients. However, metabolic changes in patients, such as HIV lipodystrophy syndrome, may occur with antiretroviral therapy. Thus, it is necessary to adopt strategies to prevent and treat lipodystrophy and other possible side effects of. We report the case of a female patient with prior antiretroviral therapy and decreased thickness of the lower limbs bilaterally, especially in knees and distal third of the legs. The sites with evidence of lipoatrophy were filled with polymethylmethacrylate, with satisfactory results and adherence by the patient.

Keywords: HIV-ASSOCIATED LIPODYSTROPHY SYNDROME; POLYMETHYL METHACRYLATE; ACQUIRED IMMUNODEFICIENCY SYNDROME.