The clinical use of combined technologies has been increasing to address the effects of skin aging on the face and other areas of the body. Poly-L-lactic acid is a biocompatible, semipermanent synthetic filler used for volume enhancement through neocollagenesis induction by fibroblast activation. Similarly, energy-based technologies, such as high-intensity focused ultrasound and microneedling radiofrequency devices, promote fat reduction and collagen contraction by heating the deep dermis. This article presents expert panel recommendations and a literature review on the topic.

Keywords: Polylactic Acid-Polyglycolic Acid Copolymer; Radiofrequency Therapy; Collagen Type I; Collagen Type III; Adipose Tissue.

This article presents practical guidelines for the synergistic use of HA and laser/energy-based technologies in facial rejuvenation. These recommendations originate from the collaborative interaction of a multidisciplinary group of physicians with experience in dermatology and plastic surgery, and can potentially be extended to treat other areas of the body, including neck and hands. The synergy between HA and lasers/intense pulsed light was recognized, emphasizing patient-tailored treatments and post-treatment care. These recommendations represent valuable guidelines, which can be adapted according to individual patient needs and to the continuous advancement of dermatological technologies.

Keywords: Lasers; Light; Rejuvenation; Hyaluronic Acid; Laser Therapy; Intense Pulsed Light Therapy.