Surg Cosmet Dermatol. 2010;2(1):63-66
Keratoacanthoma may be easily mistaken with squamous cell carcinoma, both clinically as well as histopathologically. However, only keratoacanthoma can regress spontaneously.We report a case of a patient with a exophytic, ulceraded, infiltrated lesion in their scalp that was initially diagnosed as a keratoacanthoma. The histopathologic examination confirmed the presence of squamous cell carcinoma, and the tomography of the skull showed that the cancer had spread within the cranium. A surgical excision with wide margins and rotation flap was conducted, followed by adjuvant chemotherapy and radiotherapy treatments.There are a great number of accounts of squamous cell carcinoma erroneously diagnosed as keratoacanthomas in the specialist literature, illustrating the difficulty in differentiating
between them.While there is no established effective method to distinguish between the two conditions, surgical excision should be the treatment of choice.
Keywords: CARCINOMA, SQUAMOUS CELL, KERATOACANTHOMA, SURGERY
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